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An evolutionary tree for invertebrate globin sequences
TLDR
The maximum parsimony tree was consistent with the available fossil record and supported the hypotheses that the primitive hemoglobin of metazoans was monomeric and that the multisubunit extracellular hemoglobins found among the Annelida and the Arthropoda represent independently derived states. Expand
HEAVY‐METAL INDUCED CHANGES IN NONPROTEINACEOUS THIOL LEVELS AND HEAVY‐METAL BINDING PEPTIDE IN TETRASELMIS TETRATHELE (PRASINOPHYCEAE)
TLDR
HPLC analyses revealed that glutathione was a major nonprotein thiol in T. tetrathele and that it was oxidized by exposing the cells to HgCl2, suggesting that it functions to scavenge heavy metals as well as thiol molecules. Expand
Studies on a new immunoactive peptide, FK-156. II. Fermentation, extraction and chemical and biological characterization.
TLDR
Pretreatment of mice or rats with this peptide protected the animals against lethal infection with Escherichia coli and resulted in prolongation of life span of tumor bearing animals. Expand
Two globin strains in the giant annelid extracellular haemoglobins.
TLDR
The isolated constituent polypeptide chains I, II, III and IV of the giant extracellular haemoglobin of the oligochaete Lumbricus terrestris were isolated and it was found that there are two strains of globin chain in the annelid extrace cellular haemoglobins. Expand
Primary structure of two linker chains of the extracellular hemoglobin from the polychaete Tylorrhynchus heterochaetus.
TLDR
Two types of linker subunits (linkers 1 and 2) of the extracellular hemoglobin of Tylorrhynchus heterochaetus have been isolated as disulfide-linked homodimers by C18 reverse-phase chromatography, and a model is proposed for the subunit structure. Expand
Studies on a new immunoactive peptide, FK-156. I. Taxonomy of the producing strains.
TLDR
Two strains of actinomycetes produce a new biologically active substance, designated FK-156, and are identified as Streptomyces olivaceogriseus sp. Expand
The calcium, copper and zinc content of some annelid extracellular haemoglobins.
TLDR
The extracellular haemoglobins of Lumbricus and Tylorrhynchus contain 50 and 61 tightly bound calcium atoms per molecule, respectively, and that of calcium is probably structural, assisting in the maintenance of the native hexagonal bilayer structure. Expand
Carbohydrate gluing, an architectural mechanism in the supramolecular structure of an annelid giant hemoglobin.
TLDR
Results show that carbohydrate acts noncovalently to glue together the components to yield the complete quaternary supramolecular structure of the giant Hb, and suggest that this carbohydrate gluing may be mediated through lectin-like carbohydrate-binding by the associated structural chains ("linkers"). Expand
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