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IL-28, IL-29 and their class II cytokine receptor IL-28R
TLDR
A family of three cytokines, designated interleukin 28A, IL-28B and IL-29, that are distantly related to type I interferons (IFNs) and the IL-10 family are identified and may serve as an alternative totype I IFNs in providing immunity to viral infection.
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function
TLDR
In vitro assays suggest that IL21 has a role in the proliferation and maturation of natural killer cell populations from bone marrow, in theiferation of mature B-cell populations co-stimulated with anti-CD40, and in the growth of T cells co- Stimulated withAnti-CD3.
Facteur 7 mammalien du type cytokine
L'invention a trait a des polypeptides mammaliens zcyto7, a des polynucleotides les codant ainsi qu'a des compositions afferentes et a des methodes reposant sur des anticorps ainsi que sur des