CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.
- J. Thompson, D. Higgins, T. Gibson
- BiologyNucleic Acids Research
- 11 November 1994
The sensitivity of the commonly used progressive multiple sequence alignment method has been greatly improved and modifications are incorporated into a new program, CLUSTAL W, which is freely available.
The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools.
- J. Thompson, T. Gibson, F. Plewniak, F. Jeanmougin, D. Higgins
- Computer Science, BiologyNucleic Acids Research
- 1 December 1997
ClUSTAL X is a new windows interface for the widely-used progressive multiple sequence alignment program CLUSTAL W, providing an integrated system for performing multiple sequence and profile alignments and analysing the results.
Clustal W and Clustal X version 2.0
- Mark A. Larkin, G. Blackshields, D. Higgins
- Computer ScienceBioinform.
- 1 November 2007
SUMMARY
The Clustal W and Clustal X multiple sequence alignment programs have been completely rewritten in C++. This will facilitate the further development of the alignment algorithms in the future…
Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
- Fabian Sievers, A. Wilm, D. Higgins
- Computer Science, BiologyMolecular Systems Biology
- 11 October 2011
A new program called Clustal Omega is described, which can align virtually any number of protein sequences quickly and that delivers accurate alignments, and which outperforms other packages in terms of execution time and quality.
Multiple sequence alignment with the Clustal series of programs
- C. Ramu, H. Sugawara, J. Thompson
- BiologyNucleic Acids Res.
- 1 July 2003
The Clustal series of programs are widely used in molecular biology for the multiple alignment of both nucleic acid and protein sequences and for preparing phylogenetic trees. The popularity of the…
Multiple sequence alignment with Clustal X.
- F. Jeanmougin, J. Thompson, M. Gouy, D. Higgins, T. Gibson
- BiologyTIBS -Trends in Biochemical Sciences. Regular ed
- 1 October 1998
Multiple Sequence Alignment Using ClustalW and ClustalX
- J. Thompson, T. Gibson, D. Higgins
- Computer ScienceCurrent Protocols in Bioinformatics
- 1 January 2003
The protocols in this unit discuss how to use ClustalX and ClUSTalW to construct an alignment, and create profile alignments by merging existing alignments.
Using CLUSTAL for multiple sequence alignments.
- D. Higgins, J. Thompson, T. Gibson
- BiologyMethods in Enzymology
- 1996
Protein disorder prediction: implications for structural proteomics.
- R. Linding, L. Jensen, F. Diella, P. Bork, T. Gibson, R. Russell
- BiologyStructure
- 1 November 2003
Ancient Protostome Origin of Chemosensory Ionotropic Glutamate Receptors and the Evolution of Insect Taste and Olfaction
It is shown that IRs are expressed in olfactory organs across Protostomia—a major branch of the animal kingdom that encompasses arthropods, nematodes, and molluscs—indicating that they represent an ancestral protostome chemosensory receptor family.
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