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Mass spectrometric dereplication of nitrogen-containing constituents of black cohosh (Cimicifuga racemosa L.).
Black cohosh preparations are popular dietary supplements among women seeking alternative treatments for menopausal complaints. For decades, triterpene glycosides and phenolic acids have dominatedExpand
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A Phenol Glucoside, Uncommon Coumarins and Flavonoids from Pelargonium sidoides DC
Structural examination of the metabolic pool of the aerial parts of Pelargonium sidoides DC has led to the isolation of two new metabolites, 4-allyl-2,5-dimethoxyphenol-1-β -D-glucopyranoside andExpand
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In vitro serotonergic activity of black cohosh and identification of N(omega)-methylserotonin as a potential active constituent.
Cimicifuga racemosa (L.) Nutt. (syn. Actaea racemosa L., black cohosh) is used to relieve menopausal hot flashes, although clinical studies have provided conflicting data, and the activeExpand
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Quantitative 1H NMR. Development and potential of an analytical method: an update.
This review continues a previous literature overview on quantitative (1)H NMR methodology and its applications in the analysis of natural products. Expand
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Importance of Purity Evaluation and the Potential of Quantitative 1H NMR as a Purity Assay
In any biomedical and chemical context, a truthful description of chemical constitution requires coverage of both structure and purity. This qualification affects all drug molecules, regardless ofExpand
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In vitro metabolic interactions between black cohosh (Cimicifuga racemosa) and tamoxifen via inhibition of cytochromes P450 2D6 and 3A4
Women who experience hot flashes as a side effect of tamoxifen (TAM) therapy often try botanical remedies such as black cohosh to alleviate these symptoms. Since pharmacological activity of TAM isExpand
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One of the most promising new technologies emerging to meet fuel efficiency and environmental challenges for mediumand heavy-duty vehicles is the hybrid drive system. Hybrid drive systems offer theExpand
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The tandem of full spin analysis and qHNMR for the quality control of botanicals exemplified with Ginkgo biloba.
Botanical dietary supplements and herbal remedies are widely used for health promotion and disease prevention. Due to the high chemical complexity of these natural products, it is essential toExpand
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Occurrence of progesterone and related animal steroids in two higher plants.
Previously, the presence of a wide variety of chemically diverse steroids has been identified in both flora and fauna. Despite the relatively small differences in chemical structures and largeExpand
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Phytochemistry of cimicifugic acids and associated bases in Cimicifuga racemosa root extracts.
INTRODUCTION Earlier studies reported serotonergic activity for cimicifugic acids (CA) isolated from Cimicifuga racemosa. The discovery of strongly basic alkaloids, cimipronidines, from the activeExpand
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