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Innate Lymphoid Cells Promote Anatomical Containment of Lymphoid-Resident Commensal Bacteria
Protecting Against a Barrier Breach In order to coexist peacefully, a “firewall” exists that keeps the commensal bacteria that reside in our intestines and associated lymphoid tissue contained.Expand
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Innate lymphoid cells regulate CD4+ T cell responses to intestinal commensal bacteria
Innate lymphoid cells (ILCs) are a recently characterized family of immune cells that have critical roles in cytokine-mediated regulation of intestinal epithelial cell barrier integrity. AlterationsExpand
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Caspase-11 Activation in Response to Bacterial Secretion Systems that Access the Host Cytosol
Inflammasome activation is important for antimicrobial defense because it induces cell death and regulates the secretion of IL-1 family cytokines, which play a critical role in inflammatoryExpand
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Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria–specific CD4+ T cells
Innate lymphoid cells keep gut T cells in check Trillions of bacteria inhabit our guts. So do many types of immune cells, including T cells, which might be expected to attack these bacteria. How,Expand
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Pyogenic liver abscess: an audit of 10 years' experience.
AIM To describe our own experience with pyogenic liver abscesses over the past 10 years and investigate the risk factors associated with failure of initial percutaneous therapy. METHODS AExpand
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Alveolar Macrophages and Neutrophils Are the Primary Reservoirs for Legionella pneumophila and Mediate Cytosolic Surveillance of Type IV Secretion
ABSTRACT Legionella pneumophila, an intracellular pathogen responsible for the severe pneumonia Legionnaires' disease, uses its dot/icm-encoded type IV secretion system (T4SS) to translocate effectorExpand
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Reliability and validity of K10 and K6 in screening depressive symptoms in Hong Kong adolescents
The current study examined the reliability and validity of Kessler 10 (K10) and Kessler 6 (K6) in screening adolescents at risk of suffering from depression. In total, 2325 Hong Kong secondary schoolExpand
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Basophils Promote Innate Lymphoid Cell Responses in Inflamed Skin
Type 2 inflammation underlies allergic diseases such as atopic dermatitis, which is characterized by the accumulation of basophils and group 2 innate lymphoid cells (ILC2s) in inflamed skin lesions.Expand
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Anatomical localization of commensal bacteria in immune cell homeostasis and disease
The mammalian gastrointestinal (GI) tract is colonized by trillions of beneficial commensal bacteria that are essential for promoting normal intestinal physiology. While the majority of commensalExpand
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Adolescent quality of life and satisfaction with care.
PURPOSE 1) To describe adolescents' responses to a client satisfaction and family-centered care survey; 2) to examine the relationship between satisfaction with health care and health-related qualityExpand
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