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BDNF induction with mild exercise in the rat hippocampus.
- H. Soya, T. Nakamura, +6 authors T. Nishijima
- Biology, Medicine
- Biochemical and biophysical research…
- 13 July 2007
Although chronic voluntary physical activity has been shown to enhance hippocampal brain-derived neurotrophic factor (BDNF) expression in animals, the effects of forced exercise on a treadmill have… Expand
Essential role for ERK2 mitogen‐activated protein kinase in placental development
- N. Hatano, Y. Mori, +7 authors M. Ogata
- Biology, Medicine
- Genes to cells : devoted to molecular & cellular…
- 1 November 2003
Background: Extracellular signal‐regulated kinase 2 (ERK2) has been implicated in cell proliferation, differentiation, and survival. However, its role in vivo remains to be determined.
Metabolic and endocrine consequences of social stress in a visible burrow system
- K. Tamashiro, M. Nguyen, T. Fujikawa, T. Xu, R. Sakai
- Medicine, Psychology
- Physiology & Behavior
- 1 February 2004
The visible burrow system (VBS) is an ethologically relevant model of social stress, which has been used to study the aggression of male rats in a social context. Previous studies using the VBS have… Expand
Brain glycogen supercompensation following exhaustive exercise
Non‐technical summary Exercise training elicits an increase in the basal level of muscular glycogen. This happens when glycogen recovers to above its basal level (supercompensation) after it… Expand
Critical role of p38 MAPK for regeneration of the sciatic nerve following crush injury in vivo
BackgroundThe physiological function of p38α, which is an isoform of p38 MAPK, has been investigated previously in several studies using pharmacological inhibitors. However, the results regarding… Expand
Protective effects of Acanthopanax senticosus Harms from Hokkaido and its components on gastric ulcer in restrained cold water stressed rats.
- T. Fujikawa, A. Yamaguchi, I. Morita, H. Takeda, S. Nishibe
- Biological & pharmaceutical bulletin
- 15 September 1996
The aim of this study is to investigate the pharmacological effect of the stem bark of Acanthopanax senticosus Harms from Hokkaido (Japanese name: Ezoukogi) in place of the root bark as a restorative… Expand
The growth hormone (GH) gene is expressed in the lateral hypothalamus: enhancement by GH-releasing hormone and repression by restraint stress.
Recent studies suggest that GH may modulate emotion, behavior, or stress response by its direct actions on the brain, and possible expression of the GH gene in the brain has been predicted. In this… Expand
Restraint stress enhances the gene expression of prolactin receptor long form at the choroid plexus.
Hormonal control of brain functions is considered to be important in the tolerance of stress, and it is now established that stress elevates serum PRL levels in male or cycling female rats. To… Expand
Eucommia leaf extract (ELE) prevents OVX-induced osteoporosis and obesity in rats.
- W. Zhang, T. Fujikawa, +4 authors A. Wada
- The American journal of Chinese medicine
- 19 July 2012
The cortex of Eucommia ulmoides Oliver is widely used to treat kidney deficiency in traditional Chinese medicine. Its leaves have recently been reported to have anti-obesity properties in metabolic… Expand
Acanthopanax senticosus Harms as a prophylactic for MPTP-induced Parkinson's disease in rats.
- T. Fujikawa, Shinji Miguchi, +4 authors K. Nakashima
- Journal of ethnopharmacology
- 28 February 2005
The aim of this study was to determine whether Acanthopanax senticosus Harms (ASH) offers protection against Parkinson's disease (PD) and its related depressive behaviors in rats administered… Expand