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Adhesive, Flexible, and Robust Polysaccharide Nanosheets Integrated for Tissue‐Defect Repair
- T. Fujie, Noriyuki Matsutani, M. Kinoshita, Y. Okamura, A. Saito, S. Takeoka
- Materials Science
- 24 August 2009
Recent developments in nanotechnology have led to a method for producing free-standing polymer nanosheets as a macromolecular organization. Compared with bulk films, the large aspect ratio of such… Expand
Myotube formation on gelatin nanofibers - multi-walled carbon nanotubes hybrid scaffolds.
- S. Ostrovidov, Xuetao Shi, +10 authors A. Khademhosseini
- Medicine, Materials Science
- 1 August 2014
Engineering functional muscle tissue requires the formation of densely packed, aligned, and mature myotubes. To enhance the formation of aligned myotubes with improved contractibility, we fabricated… Expand
Ultra-thin conductive free-standing PEDOT/PSS nanofilms
Free-standing conductive ultra-thin films based on poly(3,4-ethylenedioxythiophene)/poly(styrenesulfonate) (PEDOT/PSS) are realized. A fabrication process based on a modified Supporting Layer… Expand
Fragmentation of poly(lactic acid) nanosheets and patchwork treatment for burn wounds.
- Y. Okamura, Koki Kabata, +6 authors S. Takeoka
- Medicine, Materials Science
- Advanced materials
- 25 January 2013
Freestanding poly(L-lactic acid) (PLLA) nanosheets are mass-produced by a simple combination of a spin-coating-assisted multi-layering process and a peeling technique. The resulting PLLA nanosheets… Expand
Development of fibrinogen gamma-chain peptide-coated, adenosine diphosphate-encapsulated liposomes as a synthetic platelet substitute.
- Y. Okamura, S. Takeoka, +5 authors M. Handa
- Journal of thrombosis and haemostasis : JTH
- 1 March 2009
BACKGROUND The dodecapeptide HHLGGAKQAGDV (H12), corresponding to the fibrinogen gamma-chain carboxy-terminal sequence (gamma 400-411), is a specific binding site of the ligand for platelet… Expand
Skeletal muscle tissue engineering: methods to form skeletal myotubes and their applications.
- S. Ostrovidov, V. Hosseini, +6 authors A. Khademhosseini
- Medicine, Biology
- Tissue engineering. Part B, Reviews
- 1 October 2014
Skeletal muscle tissue engineering (SMTE) aims to repair or regenerate defective skeletal muscle tissue lost by traumatic injury, tumor ablation, or muscular disease. However, two decades after the… Expand
Dual therapeutic action of antibiotic-loaded nanosheets for the treatment of gastrointestinal tissue defects.
An ultra-thin polymer film (nanosheet) composed of polysaccharides (i.e., polysaccharide nanosheet) provides sufficient adhesiveness, flexibility and robustness to act as an effective wound dressing.… Expand
Three-dimensional co-culture of C2C12/PC12 cells improves skeletal muscle tissue formation and function.
- S. Ostrovidov, S. Ahadian, +9 authors A. Khademhosseini
- Biology, Medicine
- Journal of tissue engineering and regenerative…
- 1 February 2017
Engineered muscle tissues demonstrate properties far from native muscle tissue. Therefore, fabrication of muscle tissues with enhanced functionalities is required to enable their use in various… Expand
Sealing effect of a polysaccharide nanosheet for murine cecal puncture.
BACKGROUND Recent developments in nanobiotechnology have led us to develop a method of producing a free-standing polymer nanosheet composed of polysaccharides (ie, polysaccharide nanosheet) with a… Expand
Adhesion and proliferation of skeletal muscle cells on single layer poly(lactic acid) ultra-thin films
- L. Ricotti, S. Taccola, +5 authors P. Dario
- Materials Science, Medicine
- Biomedical microdevices
- 16 June 2010
An increasing interest in bio-hybrid systems and cell-material interactions is evident in the last years. This leads towards the development of new nano-structured devices and the assessment of their… Expand