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Meta‐analysis of structural MRI studies in children and adults with attention deficit hyperactivity disorder indicates treatment effects
Frodl T, Skokauskas N. Meta‐analysis of structural MRI studies in children and adults with attention deficit hyperactivity disorder indicates treatment effects.
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How does the brain deal with cumulative stress? A review with focus on developmental stress, HPA axis function and hippocampal structure in humans
There is evidence that excessive stress exposure of the brain, mediated through the neurotoxic effects of cortisol and possibly neuroinflammation, causes damage to brain structure and function: theExpand
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The hippocampus in major depression: evidence for the convergence of the bench and bedside in psychiatric research?
Major depressive disorder (MDD) has until recently been conceptualized as an episodic disorder associated with ‘chemical imbalances’ but no permanent brain changes. Evidence has emerged in the pastExpand
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Association of the brain-derived neurotrophic factor Val66Met polymorphism with reduced hippocampal volumes in major depression.
CONTEXT Brain-derived neurotrophic factor (BDNF) modulates hippocampal plasticity, which is believed to be altered in patients with major depression. OBJECTIVE To examine the effect of the BDNFExpand
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Hippocampal changes in patients with a first episode of major depression.
OBJECTIVE Previous work suggests that patients with unipolar depression may have structural as well as functional abnormalities in limbic-thalamic-cortical networks, which are hypothesized toExpand
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Depression-related variation in brain morphology over 3 years: effects of stress?
CONTEXT Results of experimental studies suggest that neuroplastic changes may occur during depressive episodes. These effects have not been confirmed in patients with depression, to our knowledge. Expand
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Larger amygdala volumes in first depressive episode as compared to recurrent major depression and healthy control subjects
BACKGROUND The aim of our study was to test the hypothesis that amygdala volumes are reduced in patients with recurrent major depression compared with first episode patients. METHODS UsingExpand
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Use of neuroanatomical pattern classification to identify subjects in at-risk mental states of psychosis and predict disease transition.
CONTEXT Identification of individuals at high risk of developing psychosis has relied on prodromal symptomatology. Recently, machine learning algorithms have been successfully used for magneticExpand
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Hippocampal and amygdala changes in patients with major depressive disorder and healthy controls during a 1-year follow-up.
BACKGROUND Although the hippocampus has been found to be smaller in patients with depression, prospective longitudinal in vivo studies are necessary to investigate whether depression can result in aExpand
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Reduced gray matter brain volumes are associated with variants of the serotonin transporter gene in major depression
The serotonergic system is involved in the pathophysiology of major depression as well as in the early central nervous system development and adult neuroplasticity. The aim of the study was toExpand
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