Potential of Plant Bioactive Compounds as SARS-CoV-2 Main Protease (Mpro) and Spike (S) Glycoprotein Inhibitors: A Molecular Docking Study
- T. Tallei, S. G. Tumilaar, T. Emran
- 7 April 2020
Since the outbreak of the COVID-19 (coronavirus disease 19) pandemic, researchers have been trying to investigate several active compounds found in plants that have the potential to inhibit the…
Covid‐19 and dengue: Double punches for dengue‐endemic countries in Asia
- H. Harapan, Mirza Ryan, R. T. Sasmono
- MedicineReviews in Medical Virology
- 18 September 2020
The issue of Covid‐19 and dengue fever misdiagnosis is raised, not only in a clinical setting but also with regards to cross‐reactivity between SARS‐CoV‐2 and DENV antibodies.
Role of Inflammatory Cytokines in COVID-19 Patients: A Review on Molecular Mechanisms, Immune Functions, Immunopathology and Immunomodulatory Drugs to Counter Cytokine Storm
- A. Rabaan, Shamsah H. Al-Ahmed, K. Dhama
- Biology, MedicineVaccines
- 29 April 2021
Light is shed on the pivotal roles played by various inflammatory markers in COVID-19-related complications and prospective anti-inflammatory and relevant immunomodulatory drugs currently in various trial phases and their possible implications are discussed.
Efficacy of Phytochemicals Derived from Avicennia officinalis for the Management of COVID-19: A Combined In Silico and Biochemical Study
- S. Mahmud, G. Paul, J. Simal-Gándara
- 1 April 2021
Phytochemicals extracted from Avicennia officinalis and evaluated their potential effects against the main protease of SARS-CoV-2 required in vitro and in vivo validation to ensure the possible inhibitory effects and pharmacological efficacy of the identified compounds.
Viral Dynamics and Real-Time RT-PCR Ct Values Correlation with Disease Severity in COVID-19
- A. Rabaan, R. Tirupathi, K. Dhama
- 1 June 2021
A revised review of the literature has been conducted to fill the knowledge gaps regarding the correlations between Ct values and severity/fatality rates of patients with COVID-19 and discusses the factors that can affect these values, such as collection technique, type of swab, sampling method, etc.
Virtual screening and molecular dynamics simulation study of plant-derived compounds to identify potential inhibitors of main protease from SARS-CoV-2
The computational drug designing approach may contribute to the development of drugs against SARS-CoV-2 by exploring root meansquare deviations, root mean square fluctuations, solvent accessible surface area, radius of gyration and hydrogen bond analysis from simulation trajectories.
Designing of a Multi-epitope Vaccine against the Structural Proteins of Marburg Virus Exploiting the Immunoinformatics Approach
- S. Sami, Kay Kay Shain Marma, T. Emran
- BiologyACS Omega
- 18 November 2021
The design and formulation of a multi-epitope vaccine based on the structural proteins of MARV employing immunoinformatics approaches suggested the vaccine constructs’ ability to regulate promising immune responses against MARV pathogenesis.
Investigation of the Pharmacological Properties of Lepidagathis hyalina Nees through Experimental Approaches
- Fowzul Islam Fahad, Niloy Barua, R. Capasso
- 25 February 2021
The current study suggests that L. hyalina could be a potential source of anti-oxidative, cytotoxic, thrombolytic, anxiolytic and antidepressant agents.
IoT Based Real-time River Water Quality Monitoring System
- M. Chowdury, T. Emran, Mohammad Shahadat Hossain
- Computer ScienceProcedia Computer Science
Superoxide dismutase: an updated review on its health benefits and industrial applications
- M. Islam, A. Rauf, Mohammad S. Mubarak
- BiologyCritical reviews in food science and nutrition
- 27 April 2021
The findings of human and animal studies that support the advantages of SOD enzyme regulations to reduce the formation of oxidative stress in various ways are discussed.