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Libri Ricevuti: IARC Monographs on the Evaluation of Carcinogenic Risks to Humans
- T. Dragani
- 1 August 1992
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs
Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. There is an international collaborative effort to identify all full-length mRNA transcripts from the… Expand
Libri Ricevuti: Iarc Monographs on the Evaluation of Carcinogenic Risks to Humans
- T. Dragani
- 1 October 1992
Cloning of mouse ptx3, a new member of the pentraxin gene family expressed at extrahepatic sites.
Pentraxins, which include C reactive protein (CRP) and serum amyloid P component (SAP), are prototypic acute phase reactants that serve as indicators of inflammatory reactions. Here we report genomic… Expand
Risk of HCC: genetic heterogeneity and complex genetics.
- T. Dragani
- Journal of hepatology
- 1 February 2010
Hepatocellular carcinoma (HCC) is a common form of cancer that arises from hepatocytes and whose risk may be affected by several known environmental factors, including hepatitis viruses, alcohol,… Expand
Transcription Deregulation at the 15q25 Locus in Association with Lung Adenocarcinoma Risk
- F. S. Falvella, A. Galvan, +7 authors T. Dragani
- Biology, Medicine
- Clinical Cancer Research
- 1 March 2009
Purpose: We characterized the candidacy of the six candidate genes mapping in the chromosome 15q25 locus, which was previously reported as associated with lung cancer risk, and confirmed the locus… Expand
Functional FGFR4 Gly388Arg polymorphism predicts prognosis in lung adenocarcinoma patients.
- M. Spinola, V. Leoni, +4 authors T. Dragani
- Journal of clinical oncology : official journal…
- 10 October 2005
PURPOSE Fibroblast growth factor receptor 4 (FGFR4) is a member of a family of transmembrane receptors with ligand-induced tyrosine kinase activity. The Gly388Arg polymorphism in the FGFR4 gene was… Expand
FGFR4 Gly388Arg polymorphism and prognosis of breast and colorectal cancer.
A functional Gly388Arg variation in the FGFR4 gene has been reported to be associated with breast and colorectal cancer prognostic parameters. To further examine the functional role of this genetic… Expand
Identification of RASSF8 as a candidate lung tumor suppressor gene
The RASSF8 gene, which maps close to the KRAS2 gene, contains a RAS-associated domain and encodes a protein that is evolutionarily conserved from fish to humans. Analysis of the RASSF8 transcript… Expand
Mouse Genome-Wide Association Mapping Needs Linkage Analysis to Avoid False-Positive Loci
We carried out genome-wide association (GWA) studies in inbred mouse strains characterized for their lung tumor susceptibility phenotypes (spontaneous or urethane-induced) with panels of 12,959 (13K)… Expand