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The epidemiology of occupational contact dermatitis.
The lack of truly epidemiologic data on OCD is illustrated and the distribution of allergic and irritant contact dermatitis in the working population is highlighted, the interrelationship between exogenous (allergens, irritants) and endogenous factors, the prognosis, the social and economic impact, and the need for intervention studies are illustrated. Expand
Occupational skin-disease data in Europe
  • T. Diepgen
  • Medicine
  • International archives of occupational and…
  • 11 April 2003
The different occupational health systems and legislations in the countries across Europe makes it difficult for one to sketch a detailed picture for the whole continent, and reliable data are hard to extract from official registries, while the problem in specific occupational groups is more pronounced. Expand
Efficacy and safety of oral alitretinoin (9‐cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double‐blind,
Background  Patients with severe chronic hand eczema (CHE) refractory to topical corticosteroids currently have limited treatment options suited for chronic use, and few controlled clinical studiesExpand
Age related, structured educational programmes for the management of atopic dermatitis in children and adolescents: multicentre, randomised controlled trial
Age related educational programmes for the control of atopic dermatitis in children and adolescents are effective in the long term management of the disease. Expand
Atopic diseases, immunoglobulin E and risk of cancer of the prostate, breast, lung and colorectum
The findings are consistent with other epidemiological evidence suggesting an increased risk of prostate cancer with atopy and indicate a complex association between atopy/atopy‐related diseases and cancer risk that varies by type of atopy‐ related disorders and the particular type of cancer under consideration. Expand
Guidelines for diagnosis, prevention and treatment of hand eczema
Topical corticosteroids are recommended as first line treatment in the management of HE, however continuous long‐term treatment beyond six weeks only when necessary and under careful medical supervision is recommended. Expand
Monitoring levels of preservative sensitivity in Europe
The current high level of sensitivity to MDBGN requires an urgent safety re‐evaluation and risk assessment update along with consideration of immediate lowering of use concentrations, especially in leave‐on products. Expand
Efficacy and safety of tacrolimus ointment compared with that of hydrocortisone butyrate ointment in adult patients with atopic dermatitis.
Skin burning and pruritus at the application site showed a higher incidence in the tacrolimus treatment groups than in the hydrocortisone butyrate group, and Laboratory parameters showed no treatment differences and no marked changes over time. Expand
Prevalence, correlates and characteristics of chronic pruritus: a population-based cross-sectional study.
This study indicates a high burden of chronic pruritus in society and its impact on quality of life and emotional well-being appears to depend on severity rather than on the presence of the symptom alone. Expand
A method for the production of cryopreserved aliquots of antigen-preloaded, mature dendritic cells ready for clinical use.
It is demonstrated that DC can effectively be loaded with antigens before cryopreservation so that it is now possible to generate antigen-preloaded, frozen DC aliquots that after thawing can be used right away. Expand