• Publications
  • Influence
Effects of damage morphology on cortical bone fragility.
Despite a general understanding that bone microdamage has distinct strain dependent morphologies, very little information exists on how different damage morphologies develop and participate in boneExpand
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Age-related change in the damage morphology of human cortical bone and its role in bone fragility.
Application of cyclic loading results in the formation of distinct strain-dependent microdamage morphologies. It is still unknown; however, how the morphology of microdamage affects age-relatedExpand
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Morphology, localization and accumulation of in vivo microdamage in human cortical bone.
In vivo, microdamage occurs in the form of linear microcracks and diffuse damage. However, it is unknown whether the age-related changes in bone quality predispose bone to form one type of damageExpand
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Age-related changes in human trabecular bone: Relationship between microstructural stress and strain and damage morphology.
Accumulation of microdamage in aging and disease can cause skeletal fragility and is one of several factors contributing to osteoporotic fractures. To better understand the role of microdamage inExpand
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In situ examination of the time-course for secondary mineralization of Haversian bone using synchrotron Fourier transform infrared microspectroscopy.
At the tissue level it is well established that the rate of remodeling is related to the degree of mineralization. However, it is unknown how long it takes for an individual bone structural unitExpand
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Efficacy of an antipathology vaccine in murine schistosomiasis administered with and without chemotherapy.
This study was undertaken to study the efficacy of praziquantel (PZQ) in potentially tolerized Schistosoma mansoni infected, egg-injected C57BL/6 mice, receiving multiple administrations of solubleExpand
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Time‐course of neuropeptide changes in peri‐ischemic zone and amygdala following focal ischemia in rats
Previously, using a middle cerebral artery occlusion model in Wistar rat, we showed autonomic disturbances similar to those seen clinically and observed striking neurochemical changes in cortical andExpand
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One year of alendronate treatment lowers microstructural stresses associated with trabecular microdamage initiation.
Alendronate, an anti-remodeling agent, is commonly used to treat patients suffering from osteoporosis by increasing bone mineral density. Though fracture risk is lowered, an increase in microdamageExpand
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The Effects of Propofol in the Area Postrema of Rats
Propofol has an antiemetic effect that may be mediated by &ggr;-aminobutyric acid (GABA) influences on the serotonin system, the mechanism of which is not known. We used three techniques,Expand
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Age-dependent fatigue behaviour of human cortical bone.
Despite a general understanding that bone quality contributes to skeletal fragility, very little information exits on the age-dependent fatigue behavior of human bone. In this study four-pointExpand
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