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Synchronous visual analysis and editing of RNA sequence and secondary structure alignments using 4SALE
BackgroundThe function of a noncoding RNA sequence is mainly determined by its secondary structure and therefore a family of noncoding RNA sequences is much more conserved on the structural levelExpand
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Re-annotating the Mycoplasma pneumoniae genome sequence: adding value, function and reading frames.
Four years after the original sequence submission, we have re-annotated the genome of Mycoplasma pneumoniae to incorporate novel data. The total number of ORFss has been increased from 677 to 688 (10Expand
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Metabolic Interdependence of Obligate Intracellular Bacteria and Their Insect Hosts
SUMMARY Mutualistic associations of obligate intracellular bacteria and insects have attracted much interest in the past few years due to the evolutionary consequences for their genome structure.Expand
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The linear chromosome of the plant-pathogenic mycoplasma 'Candidatus Phytoplasma mali'
BackgroundPhytoplasmas are insect-transmitted, uncultivable bacterial plant pathogens that cause diseases in hundreds of economically important plants. They represent a monophyletic group within theExpand
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Phylogeny of Firmicutes with special reference to Mycoplasma (Mollicutes) as inferred from phosphoglycerate kinase amino acid sequence data.
The phylogenetic position of the Mollicutes has been re-examined by using phosphoglycerate kinase (Pgk) amino acid sequences. Hitherto unpublished sequences from Mycoplasma mycoides subsp. mycoides,Expand
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Predicting function: from genes to genomes and back.
Predicting function from sequence using computational tools is a highly complicated procedure that is generally done for each gene individually. This review focuses on the added value that isExpand
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Pathway alignment: application to the comparative analysis of glycolytic enzymes.
Comparative analysis of metabolic pathways in different genomes yields important information on their evolution, on pharmacological targets and on biotechnological applications. In this study onExpand
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An Integrated View of Gene Expression and Solute Profiles of Arabidopsis Tumors: A Genome-Wide Approach[W]
Transformation of plant cells with T-DNA of virulent agrobacteria is one of the most extreme triggers of developmental changes in higher plants. For rapid growth and development of resulting tumors,Expand
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Isolation and molecular characterization of a surface‐bound proteinase of Entamoeba histolytica
Major pathogenic functions of Entamoeba histolytica involved in destruction of host tissues are the degradation of extracellular matrix proteins mediated by secreted cysteine proteinases andExpand
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Improving genetic algorithms for protein folding simulations by systematic crossover.
To improve protein folding simulations, we investigated a new search strategy in combination with the simple genetic algorithm on a two-dimensional lattice model. This search strategy, we calledExpand
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