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Updating the effects of fatty acids on skeletal muscle
In this review we updated the fatty acid (FA) effects on skeletal muscle metabolism. Abnormal FA availability induces insulin resistance and accounts for several of its symptoms and complications.Expand
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Activation of survival and apoptotic signaling pathways in lymphocytes exposed to palmitic acid
The toxicity of palmitic acid (PA) towards a human T‐lymphocyte cell line (Jurkat) has been previously investigated but the mechanism(s) of PA action were unknown. In the current study, Jurkat cellsExpand
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Modulation of bone morphogenetic protein-9 expression and processing by insulin, glucose, and glucocorticoids: possible candidate for hepatic insulin-sensitizing substance.
Bone morphogenetic protein 9 (BMP-9), a member of the TGF-beta superfamily predominantly expressed in nonparenchymal liver cells, has been demonstrated to improve glucose homeostasis in diabeticExpand
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Involvement of eukaryotic translation initiation factor 5A (eIF5A) in skeletal muscle stem cell differentiation
The eukaryotic translation initiation factor 5A (eIF5A) contains a special amino acid residue named hypusine that is required for its activity, being produced by a post‐translational modificationExpand
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Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2.
In response to a range of environmental stresses, phosphorylation of the alpha subunit of the translation initiation factor 2 (eIF2α) represses general protein synthesis coincident with increasedExpand
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Topical Dexamethasone Administration Impairs Protein Synthesis and Neuronal Regeneration in the Olfactory Epithelium
Chronic inflammatory process in the nasal mucosa is correlated with poor smell perception. Over-activation of immune cells in the olfactory epithelium (OE) is generally associated with loss ofExpand
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ESTUDO DO CONTROLE TRADUCIONAL DE PPAR DURANTE O PROCESSO DE DIFERENCIAÇÃO DE MACRÓFAGOS
Cambiaghi TD. Translation control of PPARβ during macrophage differentiation [Thesis]. São Paulo: Instituto de Ciências Biomédicas da Universidade de São Paulo; 2009. The peroxisomeExpand