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Genome sequencing and analysis of Aspergillus oryzae
TLDR
Specific expansion of genes for secretory hydrolytic enzymes, amino acid metabolism and amino acid/sugar uptake transporters supports the idea that A. oryzae is an ideal microorganism for fermentation. Expand
Clustered Pathway Genes in Aflatoxin Biosynthesis
TLDR
Aflatoxins, a group of polyketide-derived furanocoumarins, are the most toxic and carcinogenic compounds among the known mycotoxins and there are only four major aflatoxINS, B1, B2, G1, and G2. Expand
A single ligand is sufficient to activate EGFR dimers
TLDR
The results unify models of vertebrate and invertebrate EGFR/ErbB signaling, imply that the tethered conformation of unliganded ErBBs evolved to prevent crosstalk among ErbBs, and establish a molecular basis for both negative cooperativity of ligand binding to vertebrate ErbBBs and the absence of active ErbbB2/HER2 homodimers in normal conditions. Expand
Identification of a maize kernel stress-related protein and its effect on aflatoxin accumulation.
TLDR
Data suggest that GLX-I may play an important role in controlling MG levels inside kernels, thereby contributing to the lower levels of aflatoxins found in resistant maize genotypes. Expand
Increased expression of Aspergillus parasiticus aflR, encoding a sequence-specific DNA-binding protein, relieves nitrate inhibition of aflatoxin biosynthesis.
TLDR
Results suggest that aflR is involved in the regulation of multiple parts of the aflatoxin biosynthetic pathway. Expand
Molecular characterization of aflR, a regulatory locus for aflatoxin biosynthesis.
TLDR
DNA hybridization of the aflR gene with genomic digests of seven polyketide-producing fungi revealed similar sequences in three other species related to A. flavus: A. parasiticus, A. oryzae, and A. sojae, suggesting that the a flR locus involves some form of antisense regulation. Expand
Identification of a Maize Kernel Pathogenesis-Related Protein and Evidence for Its Involvement in Resistance to Aspergillus flavus Infection and Aflatoxin Production.
TLDR
Evidence suggests that ZmPR-10 plays a role in kernel resistance of maize against fungal infection and aflatoxin production by inhibiting fungal growth of A. flavus. Expand
Bacillomycin D: an iturin with antifungal activity against Aspergillus flavus
TLDR
Bacillus subtilis AU195 was selected from a collection of isolates with antagonistic activity against A. flavus in a search for an antifungal peptide with a high activity against Aspergillus flavus. Expand
United States Department of Agriculture-Agricultural Research Service research on pre-harvest prevention of mycotoxins and mycotoxigenic fungi in US crops.
TLDR
Research accomplished by Agricultural Research Service (ARS) laboratories on control of pre-harvest toxin contamination by using biocontrol, host-plant resistance enhancement and integrated management systems is highlighted. Expand
Comparative mapping of aflatoxin pathway gene clusters in Aspergillus parasiticus and Aspergillus flavus.
TLDR
The physical distances (in kilobase pairs) and the directions of transcription of these genes have been determined for both aflatoxigenic species and the order is related to the order in enzymatic steps required for aflatoxin biosynthesis. Expand
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