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MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, and ORP9 expression in oxLDL-stimulated monocyte/macrophages.
AIMS The inflammatory responses of monocytes/macrophages and the stimulation of lipid uptake into these cells by oxidized low density lipoprotein (oxLDL) are critical to the initiation andExpand
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An RNA interference screen uncovers a new molecule in stem cell self-renewal and long-term regeneration
Adult stem cells sustain tissue maintenance and regeneration throughout the lifetime of an animal. These cells often reside in specific signalling niches that orchestrate the stem cell’s balancingExpand
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Sleep duration in Chinese adolescents: biological, environmental, and behavioral predictors.
OBJECTIVE To examine sleep duration-related risk factors from multidimensional domains among Chinese adolescents. METHODS A random sample of 4801 adolescents aged 11-20 years participated in aExpand
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Metabolism of the Neonicotinoid insecticides acetamiprid and thiacloprid by the yeast Rhodotorula mucilaginosa strain IM-2.
A yeast identified as Rhodotorula mucilaginosa strain IM-2 was able to degrade acetamiprid (AAP) and thiacloprid (THI) in sucrose mineral salt medium with half-lives of 3.7 and 14.8 days,Expand
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N-demethylation of neonicotinoid insecticide acetamiprid by bacterium Stenotrophomonas maltophilia CGMCC 1.1788
Our previous study found that Stenotrophomonas maltophilia CGMCC 1.1788 could hydroxylate imidacloprid (IMI) to 5-hydroxy IMI. Here we first report that S. maltophilia CGMCC 1.1788 can demethylateExpand
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Absorption and excretion of luteolin and apigenin in rats after oral administration of Chrysanthemum morifolium extract.
Chrysanthemum morifolium extract (CME) has the protective effect on cardiovascular diseases. Luteolin and apigenin are two major bioactive components in vivo when CME is orally administrated toExpand
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Neuroprotective effect of osthole against oxygen and glucose deprivation in rat cortical neurons: involvement of mitogen-activated protein kinase pathway
Osthole, a bioactive simple coumarin derivative extracted from many medicinal plants such as Cnidium monnieri (L.) Cusson, exerts a broad spectrum of pharmacological activities and is considered toExpand
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CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation.
Immune checkpoint blockade, exemplified by antibodies targeting the PD-1 receptor, can induce durable tumor regressions in some patients. To enhance the efficacy of existing immunotherapies, weExpand
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Analysis of immunomodulating nitric oxide, iNOS and cytokines mRNA in mouse macrophages induced by microcystin-LR.
Microcystins (MCs) are the toxic molecules produced by common cyanobacterium in freshwater blooms. Their toxicities have brought severe health issues to livestock and human being. Microcystin-LRExpand
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Nucleocytoplasmic Shuttling of JAZ, a New Cargo Protein for Exportin-5
ABSTRACT Exportin-5 is a nuclear export receptor for certain classes of double-stranded RNA (dsRNA), including pre-micro-RNAs, viral hairpin RNAs, and some tRNAs. It can also export the RNA bindingExpand
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