A method for assessing the quality of a randomized control trial.
- T. Chalmers, H. Smith, A. Ambroz
- MedicineControlled Clinical Trials
- 1 May 1981
Appraisal of methods for the study of chemotherapy of cancer in man: Comparative therapeutic trial of nitrogen mustard and triethylene thiophosphoramide
- C. Zubrod, M. Schneiderman, A. Owens
- Medicine
- 1960
Neurolytic Celiac Plexus Block for Treatment of Cancer Pain: A Meta-Analysis
- E. Eisenberg, D. Carr, T. Chalmers
- MedicineAnesthesia and Analgesia
- 1 February 1995
A meta-analysis of the efficacy and safety of neurolytic celiac plexus block (NCPB) for cancer pain suggests that NCPB has long-lasting benefit for 70%-90% of patients with pancreatic and other intraabdominal cancers, regardless of the technique used.
Cumulative meta-analysis of therapeutic trials for myocardial infarction.
- J. Lau, E. Antman, J. Jimenez-Silva, B. Kupelnick, F. Mosteller, T. Chalmers
- Medicine, PsychologyNew England Journal of Medicine
- 23 July 1992
Cumulative meta-analysis of therapeutic trials facilitates the determination of clinical efficacy and harm and may be helpful in tracking trials, planning future trials, and making clinical recommendations for therapy.
Effect of coronary artery bypass graft surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration
- S. Yusuf, D. Zucker, T. Chalmers
- MedicineThe Lancet
- 27 August 1994
Ascorbic acid for the common cold. A prophylactic and therapeutic trial.
- T. Karlowski, T. Chalmers, L. Frenkel, A. Kapikian, T. Lewis, J. Lynch
- MedicineJAMA
- 10 March 1975
Analysis of data showed that ascorbic acid had at best only a minor influence on the duration and severity of colds, and that the effects demonstrated might be explained equally well by a break in the double blind.
Meta-analyses of randomized controlled trials.
- H. Sacks, J. Berrier, D. Reitman, V. A. Ancona-Berk, T. Chalmers
- PsychologyNew England Journal of Medicine
- 19 February 1987
It is concluded that an urgent need exists for improved methods in literature searching, quality evaluation of trials, and synthesizing of the results.
The Comparative Effects of Postoperative Analgesic Therapies on Pulmonary Outcome: Cumulative Meta-Analyses of Randomized, Controlled Trials
- J. Ballantyne, D. Carr, F. Mosteller
- MedicineAnesthesia and Analgesia
- 1 March 1998
Meta-analyses of randomized, control trials confirm that postoperative epidural pain control can significantly decrease the incidence of pulmonary morbidity and support the utility of epidural analgesia for reducing postoperativemonary morbidity but do not support the use of surrogate measures of pulmonary outcome as predictors or determinants of pulmonary mortality in postoperative patients.
A comparison of results of meta-analyses of randomized control trials and recommendations of clinical experts. Treatments for myocardial infarction.
- E. Antman, J. Lau, B. Kupelnick, F. Mosteller, T. Chalmers
- MedicineJAMA
- 8 July 1992
Finding and analyzing all therapeutic trials in a given field has become such a difficult and specialized task that the clinical experts called on to summarize the evidence in a timely fashion need access to better databases and new statistical techniques to assist them.
Randomized versus historical controls for clinical trials.
- H. Sacks, T. Chalmers, H. Smith
- Medicine, BiologyAmerican Journal of Medicine
- 1 February 1982
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