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Polymicrobial etiology of acute pelvic inflammatory disease.
- D. Eschenbach, T. Buchanan, +7 authors K. Holmes
- The New England journal of medicine
- 24 July 1975
Tuboperitoneal gonococcal infection probably causes pelvic inflammatory disease in most patients with cervical gonitiscal infection, whereas polymicrobial tuboperitoneAL infection probably cause most nongonococcal cases. Expand
Confirmation of association of protein I serotype of Neisseria gonorrhoeae with ability to cause disseminated infection
By using the same serotyping system, this work confirmed the association between serotypes 1 and 2 of protein I of the outer membrane and both disseminated infection and serum resistance in strains from North Carolina. Expand
HIV-1 gag-specific cytotoxic T lymphocytes recognize multiple highly conserved epitopes. Fine specificity of the gag-specific response defined by using unstimulated peripheral blood mononuclear cells…
The identification of multiple relatively conserved epitopes in the HIV-1 gag protein and the heterogeneity of CTL responses to this protein may have important implications for vaccine development and the understanding of AIDS pathogenesis. Expand
Etiology of nongonococcal urethritis. Evidence for Chlamydia trachomatis and Ureaplasma urealyticum.
C culture, serology, and response to therapy support the etiologic role of chlamydia in nongonococcal urethritis (NGU) and suggest U. unrealyticum may cause many cases ofChlamydia-netative NGU. Expand
Amine content of vaginal fluid from untreated and treated patients with nonspecific vaginitis.
- K. C. Chen, P. S. Forsyth, T. Buchanan, K. Holmes
- The Journal of clinical investigation
- 1 May 1979
Analysis of vaginal washings from patients with nonspecific vaginitis suggests that a symbiotic relationship may exist between H. vaginalis and other vaginal flora in patients with NSV. Expand
2-mercaptoethanol Brucella agglutination test: usefulness for predicting recovery from brucellosis
The 2-mercaptoethanol brucella agglutination test is superior to the standard tube test in determining the adequacy of antibiotic therapy, and a negative 2ME test is strong evidence against a diagnosis of chronic brucellosis. Expand
Identification of overlapping HLA class I-restricted cytotoxic T cell epitopes in a conserved region of the human immunodeficiency virus type 1 envelope glycoprotein: definition of minimum epitopes…
- R. Johnson, A. Trocha, T. Buchanan, B. Walker
- Biology, Medicine
- The Journal of experimental medicine
- 1 April 1992
The identification of two overlapping CTL epitopes in a highly conserved region of the HIV-1 transmembrane envelope protein, gp41, using CTL clones derived from two seropositive subjects suggests that natural sequence variation may lead to escape from immune detection by HIV- 1-specific CTL, and may facilitate the definition of allele-specific motifs. Expand
Antigen-specific serotyping of Neisseria gonorrhoeae: characterization based upon principal outer membrane protein
Principal outer membrane protein (protein I) of Neisseria gonorrhoeae was prepared nearly free of lipopolysaccharide (LPS) and substantially purified from other membrane proteins by chromatography of… Expand
Serology of Neisseria gonorrhoeae: coagglutination serogroups WI and WII/III correspond to different outer membrane protein I molecules
Two different outer membrane protein I molecules seem to exist which are mutually exclusive in Neisseria gonorrhoeae, and Protein IA molecules contain the antigens recognized as serogroup WI, and protein IB molecules contain those that characterize serogroups WII and WIII. Expand