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Treating Clostridium difficile infection with fecal microbiota transplantation.
Clostridium difficile infection is increasing in incidence, severity, and mortality. Treatment options are limited and appear to be losing efficacy. Recurrent disease is especially challenging;Expand
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Multidonor intensive faecal microbiota transplantation for active ulcerative colitis: a randomised placebo-controlled trial
BACKGROUND The intestinal microbiota is implicated in the pathogenesis of ulcerative colitis. Faecal microbiota transplantation is a novel form of therapeutic microbial manipulation, but its efficacyExpand
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Fecal Microbiota Transplant for Treatment of Clostridium difficile Infection in Immunocompromised Patients
OBJECTIVES:Patients who are immunocompromised (IC) are at increased risk of Clostridium difficile infection (CDI), which has increased to epidemic proportions over the past decade. Fecal microbiotaExpand
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Fecal microbiota transplantation and emerging applications
Fecal microbiota transplantation (FMT) has been utilized sporadically for over 50 years. In the past few years, Clostridium difficile infection (CDI) epidemics in the USA and Europe have resulted inExpand
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Human interdigestive motility: variations in patterns from esophagus to colon.
In most fasting mammals, motility of the foregut and small intestine undergoes regular cycles of activity. Much of the expanding knowledge of this phenomenon comes from species other than humans;Expand
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Treatment of Ulcerative Colitis Using Fecal Bacteriotherapy
Background Although the etiology of idiopathic ulcerative colitis (UC) remains poorly understood, the intestinal flora is suspected to play an important role. Specific, consistent abnormalities inExpand
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Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study
BackgroundAutism spectrum disorders (ASD) are complex neurobiological disorders that impair social interactions and communication and lead to restricted, repetitive, and stereotyped patterns ofExpand
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Durable Alteration of the Colonic Microbiota by the Administration of Donor Fecal Flora
Goals To determine whether fecal bacteriotherapy results in a durable beneficial change in the colonic microbiota of patients with flora-related disorders. Background Earlier studies have implicatedExpand
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Long-term Follow-up Study of Fecal Microbiota Transplantation for Severe and/or Complicated Clostridium difficile Infection: A Multicenter Experience
Goal:Our aim was to investigate fecal microbiota transplantation (FMT) efficacy in patients with severe and/or complicated Clostridium difficile infection (CDI). Background:FMT is successful forExpand
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Bacteriotherapy Using Fecal Flora: Toying With Human Motions
The intestinal flora may play a key role in the pathogenesis of certain gastrointestinal (GI) diseases. Components of bowel flora such as Lactobacillus acidophilus and Bifidobacterium bifidus haveExpand
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