• Publications
  • Influence
The Protein Data Bank
The Protein Data Bank [PDB; Berman, Westbrook et al. (2000), Nucleic Acids Res. 28, 235-242; http://www.pdb.org/] is the single worldwide archive of primary structural data of biological macromolecules. Expand
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The Protein Data Bank and the challenge of structural genomics
The PDB has created systems for the processing, exchange, query, and distribution of data that will enable many aspects of high throughput structural genomics.
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The Protein Data Bank: unifying the archive
The Protein Data Bank (PDB; http://www.rcsb.org/) is the single worldwide archive of structural data of biological macromolecules. Expand
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The Protein Data Bank.
The Protein Data Bank (PDB; http://www.rcsb.org/pdb/ ) is the single worldwide archive of structural data of biological macromolecules. Expand
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Thermodynamics of enzyme-catalyzed reactions - a database for quantitative biochemistry
The Thermodynamics of Enzyme-Catalyzed Reactions Database (TECRDB) is a comprehensive collection of thermodynamic data on enzyme-catalyzed reactions. Expand
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Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design.
Cathepsin D (EC is a lysosomal protease suspected to play important roles in protein catabolism, antigen processing, degenerative diseases, and breast cancer progression. Determination ofExpand
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Structure of tyrosyl-tRNA synthetase refined at 2.3 A resolution. Interaction of the enzyme with the tyrosyl adenylate intermediate.
The crystal structure of tyrosyl-tRNA synthetase (EC from Bacillus stearothermophilus has been refined to a crystallographic R-factor of 22.6% at 2.3 A resolution using a restrainedExpand
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Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum.
  • A. Silva, A. Lee, +11 authors J. Erickson
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 17 September 1996
Plasmodium falciparum is the major causative agent of malaria, a disease of worldwide importance. Resistance to current drugs such as chloroquine and mefloquine is spreading at an alarming rate, andExpand
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The Protein Data Bank, 1999–
In 1998, members of the Research Collaboratory for Structural Bioinformatics became the managers of the Protein Data Bank archive. Expand
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Selection and analysis of human immunodeficiency virus type 1 variants with increased resistance to ABT-538, a novel protease inhibitor.
Inhibitors of the human immunodeficiency virus protease represent a promising new class of antiretroviral drugs for the treatment of AIDS. We now report the in vitro selection of viral variants withExpand
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