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Effect of antioxidants on apoptosis induced by influenza virus infection: inhibition of viral gene replication and transcription with pyrrolidine dithiocarbamate.
TLDR
Results suggested that PDTC inhibited apoptosis by inhibiting viral macromolecule synthesis rather than through its antioxidant effect, because Trolox did not inhibit apoptosis or IV production, although ROS overproduction was inhibited. Expand
Possible Roles of Proinflammatory and Chemoattractive Cytokines Produced by Human Fetal Membrane Cells in the Pathology of Adverse Pregnancy Outcomes Associated with Influenza Virus Infection
TLDR
Te lessons from pandemic H1N1 2009 in pregnancy are reviewed, possible roles of cytokines produced by human fetal membranes in the pathology of adverse pregnancy outcomes associated with influenza virus infection are reviewed and cytokines postulated to associate with human parturition are reviewed. Expand
Sequential analysis of gene expression after an osteogenic stimulus: c-fos expression is induced in osteocytes.
We have recently developed an experimental model whereby mechanical stimulation induces osteogenesis in the caudal vertebrae of rats. We used this model to assess expression of genes induced byExpand
Progressive apoptosis in chorion laeve trophoblast cells of human fetal membrane tissues during in vitro incubation is suppressed by antioxidative reagents.
TLDR
The results suggest that apoptotic cell death of the trophoblast layer of chorion tissues may be induced through intracellular oxidative stress at the stage of parturition. Expand
Suppression of apoptotic cell death progressed in vitro with incubation of the chorion laeve tissues of human fetal membrane by glucocorticoid.
TLDR
It is revealed that a substantial proportion of trophoblast cells in the chorion laeve of human fetal membranes are induced to undergo apoptosis at the end of pregnancy, and that the apoptosis progresses rapidly in vitro as the incubation period increases. Expand
Induction of pro-inflammatory cytokine gene expression and apoptosis in human chorion cells of fetal membranes by influenza virus infection: possible implications for maintenance and interruption of
TLDR
An accumulating number of evidence suggests that interactive reactions between fetal membrane chorion cells and maternal monocytes/macrophages may play a critical role in defense barriers against the virus infection. Expand
Human gastric signet ring carcinoma (KATO-III) cell apoptosis induced by Vitex agnus-castus fruit extract through intracellular oxidative stress.
TLDR
It is demonstrated that intracellular oxidative stress and mitochondrial membrane damage is responsible for Vitex-induced apoptosis, which may be mediated by a diminution of reduced type glutathione within the cell. Expand
Apoptosis in cultured human fetal membrane cells infected with influenza virus.
TLDR
The results suggest that both chorions and amnion cells become infected with influenza virus, but that influenza virus infection induces apoptosis in chorion, but not typical apoptosis characterized by DNA ladder formation in amnions. Expand
Differential mRNA expression of inflammatory cytokines in cultured human fetal membrane cells responding to influenza virus infection.
TLDR
The results indicated that chorion cells may play a role in defense against IV through an antiviral immune response and apoptosis to eliminate own cells and viral pathogens in infected organs, whereas amnion cells do not play such a role. Expand
Secretion of bioactive interleukin-6 and tumor necrosis factor-alpha proteins from primary cultured human fetal membrane chorion cells infected with influenza virus.
TLDR
A possibility that the secretion of bioactive IL-6 and TNF-alpha proteins from fetal membrane chorion cells is implicated in the pathogenesis of premature delivery during influenza virus infection is suggested. Expand
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