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Modified telomeric repeat amplification protocol: a quantitative radioactive assay for telomerase without using electrophoresis.
A polymerase chain reaction (PCR)-based radioactive telomerase assay was developed in our laboratory which is quantitative and does not require electrophoretic evaluation (designated as TP-TRAP; it
Effect of increasing thiolation of the polycytidylic acid strand of poly I: poly C on the α, β and γ interferon-inducing properties, antiviral and antiproliferative activities
Double-stranded RNAs induce interferons and cause the development of antiviral and antiproliferative activities. Antiviral activity is related to the production of interferons and other proteins that
Calvacin: A New Antitumor Agent.
Potent inhibition of HIV-1 entry by (s4dU)35.
The studies identify (s(4)dU)(35) as a potential novel HIV entry inhibitor that may have utility as either a systemic antiretroviral or as a preventing agent for HIV transmission.
Synthetic porphyrins. I. Synthesis and spectra of some para‐substituted meso ‐ Tetraphenylporphines
A series of derivatives of meso-tetraphenylporphine, with neutral, acidic and basic functional groups, has been prepared. Several of these compounds were synthesized directly via the Rothemund
The activation of murine macrophages and natural killer cells by the partially thiolated double stranded RNA poly(I)-mercapto poly(C).
There was a significant correlation between the immunostimulatory potency of these dsRNAs and their experimentally determined melting temperatures and percent hyperchromicity upon thermal denaturation.