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Modified telomeric repeat amplification protocol: a quantitative radioactive assay for telomerase without using electrophoresis.
- I. Szatmári, S. Tokés, C. Dunn, T. Bardos, J. Aradi
- Biology, Medicine
- Analytical biochemistry
- 15 June 2000
A polymerase chain reaction (PCR)-based radioactive telomerase assay was developed in our laboratory which is quantitative and does not require electrophoretic evaluation (designated as TP-TRAP; it… Expand
Effect of increasing thiolation of the polycytidylic acid strand of poly I: poly C on the α, β and γ interferon-inducing properties, antiviral and antiproliferative activities
Double-stranded RNAs induce interferons and cause the development of antiviral and antiproliferative activities. Antiviral activity is related to the production of interferons and other proteins that… Expand
Calvacin: A New Antitumor Agent.
Synthetic porphyrins. I. Synthesis and spectra of some para‐substituted meso ‐ Tetraphenylporphines
A series of derivatives of meso-tetraphenylporphine, with neutral, acidic and basic functional groups, has been prepared. Several of these compounds were synthesized directly via the Rothemund… Expand
The activation of murine macrophages and natural killer cells by the partially thiolated double stranded RNA poly(I)-mercapto poly(C).
- P. Cavanaugh, Y. K. Ho, T. Bardos
- Chemistry, Medicine
- Research communications in molecular pathology…
- 1 February 1996
Partially thiolated analogs of the biological response modifier poly I.poly C (pI.pC) were synthesized. Each of these analogs (pI.MPC) contained a partially thiolated polycytidylate (MPC) strand… Expand
Inhibition of DNA polymerases from RNA tumor viruses by novel template analogues: partially thiolated polycytidylic acid.
CHEMICAL AND ENZYMATIC METHODS IN THE SYNTHESIS OF MODIFIED POLYNUCLEOTIDES
Synthesis of New Nucleoside Phosphoraziridines as Potential Site- Directed Antineoplastic Agents.
SYNTHESIS AND INHIBITION ANALYSIS OF 2(4)-IMINO-4(2)-AMINO-2,4-DIDEOXYRIBOFLAVIN, A DUAL ANTAGONIST OF RIBOFLAVIN AND FOLINIC ACID
Comparative study of the thymidine kinase and thymidylate kinase activities and of the feedbach inhibition of thymidine kinase in normal and neoplastic human tissue.
SUMMARYActivitylevelsofthymidinekinaseandthymidylate kinaseweredetermined inextractsfrom23matchedhumanneoplasticandnormaltissuepairs.Thymidinekinaseactivitywashigherinthetumorthaninthecorresponding… Expand