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Process optimization for antifungal chitinase production by Trichoderma harzianum
Abstract Single-parameter optimization was carried out for the production of chitinase using a soil isolate belonging to Trichoderma harzianum in solid-state fermentation. Maximum chitinase activityExpand
Quinonoid compounds via reactions of lawsone and 2-aminonaphthoquinone with α-bromonitroalkenes and nitroallylic acetates: Structural diversity by C-ring modification and cytotoxic evaluation against
Morita-Baylis-Hillman acetates and α-bromonitroalkenes have been employed in cascade reactions with lawsone and 2-aminonaphthoquinone for the one-pot synthesis of heterocycle fused quinonoidExpand
Recent developments in Tsuji-Wacker oxidation
Abstract Tsuji-Wacker oxidation is a palladium catalyzed aerobic oxidation of olefins which serves as a potential strategy for the synthesis of carbonyl compounds. Functionalized terminal olefins areExpand
Synthesis of Functionalized Pyrazoles via 1,3-Dipolar Cycloaddition of α-Diazo-β-ketophosphonates, Sufones and Esters with Electron-Deficient Alkenes.
1,3-Dipolar cycloaddition of diazo compounds with olefinic substrates is a promising atom-economic strategy for the construction of functionalized pyrazoles. Over the last few years, our group hasExpand
Synthesis of Quinone‐Based N‐Sulfonyl‐1,2,3‐triazoles: Chemical Reactivity of Rh(II) Azavinyl Carbenes and Antitumor Activity
Quinone-based N-sulfonyl-1,2,3-triazoles were synthesized by click chemistry and subsequently evaluated against eight types of cancer cell lines. Some of the compounds exhibited potent cytotoxicityExpand
Synthesis of Spiro- and Fused Heterocycles via (4+4) Annulation of Sulfonylphthalide with o-Hydroxystyrenyl Derivatives.
An expedient one-pot protocol for the synthesis of functionalized benzofuran containing fused and spiro-heterocycles has been accomplished by the modified Hauser-Kraus (HK) annulation ofExpand
A general platform for antibody purification utilizing engineered-micelles
ABSTRACT We introduce a new concept and potentially general platform for antibody (Ab) purification that does not rely on chromatography or specific ligands (e.g., Protein A); rather, it makes use ofExpand
Transition Metal Free Intramolecular Approach for the Synthesis of Cyclopenta[b]chromene Derivatives From Phenol Substituted Fulvene Derived Azabicyclic Olefins
A facile route towards the synthesis of cyclopentene fused chromene derivatives from strained phenol substituted fulvene derived bicyclic hydrazines is described. The reaction is proceeding throughExpand
Synthesis of Functionalized Thieno[2,3-b]indoles via One-Pot Reaction of Indoline-2-thiones with Morita–Baylis–Hillman and Rauhut–Currier Adducts of Nitroalkenes
A straightforward protocol for the synthesis of functionalized thieno[2,3-b]indoles by base-mediated [3 + 2]-annulation of indoline-2-thione with Morita–Baylis–Hillman and Rauhut–Currier adducts ofExpand