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Analysis of Sterols
1. Nomenclature and Biosynthesis of Sterols and Related Compounds. 2. Extraction of Sterols from Tissues. 3. Initial Separation Methods. 4. HPLC of Sterols. 5. Gas-Liquid Chromatography of Sterols.Expand
Azaphilones, furanoisophthalides, and amino acids from the extracts of Monascus pilosus-fermented rice (red-mold rice) and their chemopreventive effects.
TLDR
Among the compounds tested, seven compounds on TPA-induced inflammation, and six compounds on EBV-EA activation, exhibited potent inhibitory effects. Expand
Triterpene alcohol and sterol ferulates from rice bran and their anti-inflammatory effects.
TLDR
Six novel feruloyl esters of triterpene alcohols and sterols, besides five known trans-ferulates, showed marked inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice, and eight free sterols examined showed weaker activity than their corresponding ferulates. Expand
Triterpene Acids from the Leaves of Perilla frutescens and Their Anti-inflammatory and Antitumor-promoting Effects
TLDR
Eight triterpene acids isolated from ethanol extracts of the leaves of red and green perilla exhibited strong antitumor-promoting activity in an in vivo two-stage carcinogenesis test of mouse tumor by using 7,12-dimethylbenz(a)anthracene (DMBA) as an initiator and TPA as a promoter. Expand
Anti-inflammatory activities of the triterpene acids from the resin of Boswellia carteri.
TLDR
Upon evaluation of 17 compounds, 1-14 and 16-18, and compound 15, semi-synthesized from 14 by acetylation, for their inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice, all of the compounds exhibited marked anti-inflammatory activity with a 50% inhibitory dose (ID(50) of 0.05-0.49 mg/ear. Expand
Anti-inflammatory, anti-tumor-promoting, and cytotoxic activities of constituents of marigold (Calendula officinalis) flowers.
TLDR
Two triterpene glycosides exhibited their most potent cytotoxic effects against colon cancer, leukemia, and melanoma cells against human cancer cell lines in vitro in the NCI Developmental Therapeutics Program. Expand
Anti-inflammatory and potential cancer chemopreventive constituents of the fruits of Morinda citrifolia (Noni).
TLDR
Upon evaluation of six compounds for inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice, four saccharide fatty acid esters exhibited potent anti-inflammatory activity, with ID50 values of 0.46-0.79 mg per ear. Expand
Anti-inflammatory and chemopreventive effects of triterpene cinnamates and acetates from shea fat.
TLDR
The biological activities of triterpene acetate and cinnamate esters, together with the exceptionally high levels of these triterpenes in shea fat, indicate that shea nuts and sheafat constitute a significant source of anti-inflammatory and anti-tumor promoting compounds. Expand
Anti-inflammatory and antitumor-promoting effects of the triterpene acids from the leaves of Eriobotrya japonica.
TLDR
Euscaphic acid exhibited marked antitumor-promoting activity in an in vivo two-stage carcinogenesis test of mouse tumor by using 7,12-dimethylbenz[a]anthracene (DMBA) as an initiator and TPA as a promoter. Expand
Anti‐Tumor‐Initiating Effects of Monascin, an Azaphilonoid Pigment from the Extract of Monascus pilosus Fermented Rice (Red‐Mold Rice)
TLDR
It is suggested that compound 1 may be valuable as potential cancer chemopreventive agent in chemical and environmental carcinogenesis. Expand
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