T. Aihara

Publications6
h-index3
Citations29
Highly Influential Citations2
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Structural and functional characterization of aspartate racemase from the acidothermophilic archaeon Picrophilus torridus
TLDR
Functional and structural characterizations of pyridoxal 5′-phosphate-independent aspartate racemase of the acidothermophilic archaeon Picrophilus torridus were performed and the intracellular existence of d-amino acids was examined, finding that both d-proline and d-alanine were observed.
Synthesis of [Gly-1]RA-VII, [Gly-2]RA-VII, and [Gly-4]RA-VII. Glycine-containing analogues of RA-VII, an antitumor bicyclic hexapeptide from Rubia plants.
TLDR
Three analogues of RA-VII (1), an antitumor bicyclic hexapeptide from Rubia plants, were synthesized and revealed that in solution the conformer structures and their ratios of analogue 4 were very similar to those of natural peptide 1, suggesting that the methyl groups at Ala-2 and Ala-4 should be essential for producing the bioactive conformation.
RA-dimer A, a novel dimeric antitumor bicyclic hexapeptide from Rubia cordifolia L.
Synthesis of [Gly-1]RA-VII, [Gly-2]RA-VII, and [Gly-4]RA-VII. Glycine-Containing Analogues of RA-VII, an Antitumor Bicyclic Hexapeptide from Rubia Plants.
RA-Dimer A, a Novel Dimeric Antitumor Bicyclic Hexapeptide from Rubia cordifolia L.
Picrophilus torridus aspartate racemase