• Publications
  • Influence
Effects of muscarinic blockade in perirhinal cortex during visual recognition.
Stimulus recognition in monkeys is severely impaired by destruction or dysfunction of the perirhinal cortex and also by systemic administration of the cholinergic-muscarinic receptor blocker,Expand
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Neural signals in the monkey ventral striatum related to motivation for juice and cocaine rewards.
1. The results of neuropsychological, neuropharmacological, and neurophysiological experiments have implicated the ventral striatum in reward-related processes. We designed a task to allow us toExpand
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The effects of physostigmine and scopolamine on recognition memory in monkeys.
The visual recognition of rhesus monkeys was evaluated by means of a delayed nonmatching-to-sample task with trial-unique objects. Each daily session consisted of two lists of 20 objects each, whichExpand
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Neuronal Signals in the Monkey Ventral Striatum Related to Progress through a Predictable Series of Trials
Single neurons in the ventral striatum of primates carry signals that are related to reward and motivation. When monkeys performed a task requiring one to three bar release trials to be completedExpand
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Comparison of the effects of scopolamine administered before and after acquisition in a test of visual recognition memory in monkeys.
The effect of scopolamine on visual recognition memory in rhesus monkeys was assessed with a delayed nonmatching-to-sample task employing trial-unique stimuli. During the acquisition phase, 40 sampleExpand
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Pharmacology of memory: cholinergic—glutamatergic interactions
  • T. Aigner
  • Biology, Medicine
  • Current Opinion in Neurobiology
  • 1 April 1995
Both acetylcholine and glutamate are now thought to play important roles in memory. Recent evidence suggests that the interaction of these two neurotransmitters may be important for some forms ofExpand
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Choice behavior in rhesus monkeys: cocaine versus food.
Rhesus monkeys were allowed to choose between intravenous injections of cocaine and food reinforcement for lever pressing. A choice trial was available every 15 minutes continuously for 8 days. TheExpand
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D-cycloserine, a partial agonist at the glycine site coupled to N-methyl-D-aspartate receptors, improves visual recognition memory in rhesus monkeys.
  • N. Matsuoka, T. Aigner
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental…
  • 1 August 1996
Strychnine-insensitive glycine binding sites have recently been shown to positively modulate N-methyl-D-aspartate (NMDA) receptors. In the present study, the effects on recognition memory ofExpand
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Visual habit formation in monkeys with neurotoxic lesions of the ventrocaudal neostriatum
Visual habit formation in monkeys, assessed by concurrent visual discrimination learning with 24-h intertrial intervals (ITI), was found earlier to be impaired by removal of the inferior temporalExpand
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MK-801 impairs recognition memory in rhesus monkeys: comparison with cholinergic drugs.
  • H. Ogura, T. Aigner
  • Psychology, Medicine
  • The Journal of pharmacology and experimental…
  • 1 July 1993
Both N-methyl-D-aspartate (NMDA) and cholinergic receptors are thought to participate in processes of learning and memory. The effects of the noncompetitive NMDA antagonistExpand
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