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AIMS We investigated whether kallikrein infusion attenuates renal injury in Dahl salt-sensitive rats with hypertension and assessed the role of bradykinin-nitric oxide axis in the renal protection using HOE-140, the bradykinin type-2 (B2) receptor specific antagonist. METHODS Subdepressor dose of purified rat urinary kallikrein (RUK) (400 ng/day) was(More)
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