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Maternal heroin abuse has been shown to result in teratogenic neurobehavioral defects in the offspring, but the underlying mechanisms remain largely unknown. This study was designed to explore the role of neuronal apoptosis in the heroin-induced neurobehavioral defects of learning and memory. Pregnant BALB/c mice were treated with either heroin or saline.(More)
Fenestration of a cranial nerve by an internal carotid artery aneurysm is rarely identified at surgical repair of intracranial aneurysms. Classically this condition is associated with visual disturbance in either acuity, fields or diplopia. We describe a patient with optic nerve fenestration by a carotico-ophthalmic artery aneurysm and discuss its likely(More)
We present a 40-year-old man with conus medullaris syndrome secondary to a cystic lesion of the ventriculus terminalis (CLVT) and review the relevant literature. The patient presented with 4 years of worsening right leg weakness, and examination showed bilateral fasciculations and hyporeflexia. MRI showed a cystic lesion at T11-12. He was managed with a(More)
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