T. Takashashi

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Recombinant human interferon-alpha (rIFN-alpha) inhibits erythropoiesis, in vivo and in vitro. In an attempt to clarify mechanisms related to this inhibition, effects of rIFN-alpha on highly purified human peripheral blood burst-forming units-erythroid (BFU-E) (20-60% purity) were compared with effects on erythroid progenitors in various stages of(More)
This study deals with the treatment by chemotherapy of carcinogen-induced tumors in the colon of rats. These tumors mimic colonic adenomatosis and carcinomatosis in man. The rats were given an intrarectal (i.r.) instillation of methylnitrosourea for producing colonic tumors, and thereafter received a long-term chemotherapy which was started on nascent(More)
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