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To solve the mystery of the life phenomenon, we must clarify when genes are expressed and how their products interact with each other. But since the amount of continuously updated knowledge on these interactions is massive and is only available in the form of published articles, an intelligent information extraction (IE) system is needed. To extract these(More)
Bacillus subtilis is the best-characterized member of the Gram-positive bacteria. Its genome of 4,214,810 base pairs comprises 4,100 protein-coding genes. Of these protein-coding genes, 53% are represented once, while a quarter of the genome corresponds to several gene families that have been greatly expanded by gene duplication, the largest family(More)
Fermionic formulae originate in the Bethe ansatz in solvable lattice models. They are specific expressions of some q-polynomials as sums of products of q-binomial coefficients. We consider the fermionic formulae associated with general non-twisted quantum affine algebra Uq(X (1) n) and discuss several aspects related to representation theories and(More)
We introduce a fermionic formula associated with any quantum affine algebra Uq(X (r) N). Guided by the interplay between corner transfer matrix and Bethe ansatz in solvable lattice models, we study several aspects related to representation theory, most crucially, the crystal basis theory. They include one dimensional sums over both finite and semi-infinite(More)
  • A Kuniba, T Takagi, And A Takenouchi
  • 2008
We formulate the inverse scattering method for a periodic box-ball system and solve the initial value problem. It is done by a synthesis of the combinatorial Bethe ansätze at q = 1 and q = 0, which provides the ultradiscrete analogue of quasi-periodic solutions in soliton equations, e.g., action-angle variables, Jacobi varieties, period matrices and so(More)
Drebrin is a development-associated neuroprotein whose cDNA into fibroblasts causes the formation of dendrite-like structures (Shirao, T., Kojima, N., and Obata, K. (1992) Neuroreport 3, 109-112). To explore molecular functions of drebrin during brain development, we purified drebrin from brains of rat embryos. Drebrin bound to actin filaments at a(More)
Mouse P19 embryonal carcinoma cells can be reproducibly differentiated into neurons and glial cells upon treatment with high concentrations of retinoic acid (RA). To understand the molecular mechanisms that control early neural differentiation, we constructed P19 cell lines carrying an insertion of a gene-trap vector containing lacZ as the reporter gene and(More)
Here we report the cloning and functional characterization of a rat novel peptide/histidine transporter (PHT1), which was expressed in the brain and the retina. The cDNA encodes the predicted protein of 572 amino acid residues with 12 putative membrane-spanning domains. The amino acid sequence has moderate homology with a nonspecific peptide transporter(More)
Although a number of bacterial gene-finding programs have been developed, there is still room for improvement especially in the area of correctly detecting translation start sites. We developed a novel bacterial gene-finding program named GeneHacker Plus. Like many others, it is based on a hidden Markov model (HMM) with duration. However, it is a 'local'(More)
To elucidate the behavior of the single ionic channels of cerebral cortical neurons during bursting activity, the effects of pentylenetetrazole (PTZ) on a single potassium channel of primary cultured cerebral cortical neurons from mice were examined. All of the examined 10-day-old primary cultured neurons of the cerebral cortex showed clear bursting(More)