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BACKGROUND AND AIMS Although the metabolic risk factors for non-alcoholic fatty liver disease (NAFLD) progression have been recognized, the role of genetic susceptibility remains a field to be explored. The aim of this study was to examine the frequency of two polymorphisms in Brazilian patients with biopsy-proven simple steatosis or non-alcoholic(More)
AIM There is no proven medical therapy for the treatment of non-alcoholic steatohepatitis (NASH). Oxidative stress and insulin resistance are the mechanisms that seem to be mostly involved in its pathogenesis. The aim of our study was to evaluate the efficacy of N-acetylcysteine (NAC) in combination with metformin (MTF) in improving the aminotransferases(More)
OBJECTIVE We correlated dietary profile and markers of visceral and somatic obesities in non-alcoholic fatty liver disease. METHODS Patients with histologically proven fatty infiltration of the liver (n = 25, 52 +/- 11 y of age, 64% women) underwent abdominal computed tomography, bioelectrical impedance, and anthropometric measurements. Insulin resistance(More)
The work presented in this paper is part of SatStat project, which is being developed in e-Geo – Geography and Regional Planning Research Centre of the Universidade Nova de Lisboa, under the framework of the European Space Agency (ESA) Announce of Opportunities for Portugal. The main goal of SatStat is to annual monitor forest areas using low resolution(More)
The methodology is based on semi-automatic extraction of features, using information from a QuickBird image and LIDAR data. The QuickBird image is suitable to delineate the different elements on the surface based on their spectral characteristics. However, this task is much more successful and richer when altimetric information is also used in the(More)
The high frequency and scope of spatial changes in cities demands ways of expediting the production and updating of large-scale geographic information. For that purpose, current and future very high spatial resolution satellite imagery (VHR) and semiautomated object-based image analysis methods may be an advantageous alternative to classical data sources(More)
Introduction. Sickle cell disease (SCD) is characterized by hemoglobin S homozygosity, leading to hemolysis and vasoocclusion. The hemolysis releases arginase I, an enzyme that decreases the bioavailability of nitric oxide, worsening the symptoms. The different SCD haplotypes are related to clinical symptoms and varied hemoglobin F (HbF) concentration. The(More)
In Portugal, updating municipal plans (1:10 000) is required every ten years. High spatial resolution imagery has shown its potential for detailed urban land cover mapping at large scales. However, shadows are a major problem in those images and especially in the case of urban environments. The purpose of this study is to develop a less time consuming and(More)
In the past few years, computer grids and clusters of computers have been widely used in order to keep up with the high computational performance required by highend applications. Also, they are especially attractive due to their good performance at relatively low cost, if compared to powerful servers and supercomputers. The same scenario can be faced on(More)