T S Kamynina

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The role of mutagenic factors in the onset of diffuse toxic goiter (DTG) was studied in 49 families of probands with DTG. The evidence obtained on the order in which the child was born in the proband's family, age of the parents at the time of DTG child delivery, implications of occupational factors in DTG onset does not rule out mutagenic effects in the(More)
The results of the family immunogenetic study compared to HLA-typing on the population-genetic level have established a population positive association which was more strong with HLA system regions B and DR (antigens B17, B35, DR5). Haplotype HLA A3, B35, DR5 may be considered as the haplotype of predisposition to diffuse toxic goiter. The strength of the(More)