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Clinical assessment of rigidity in parkinsonian patients is largely qualitative. The reliability and validity of the assessments are sometimes in doubt. Several "engineering" methods of quantifying rigidity have been described, but none has been adopted into general clinical practice. A possible reason is that these methods differ in crucial aspects from(More)
1 Introduction The latency of the major component of the auditory evoked neuromagnetic field, the M100 or N1m, is sensitive to acoustical and perceptual attributes of the presented stimulus [1-3]. In particular the latency depends upon stimulus intensity, frequency and spectral complexity. Thus latency variation has been proposed as an objective metric of(More)
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