General medicine department,Father Muller Medical College/Rajiv Gandhi university health sciences/, India
Overview of data, obtained in recent years, concerning the mechanistic aspects, the catalyzed versions of α-Aminophosphonates by different reactions namely Kabachnik-Fields reaction, Mannich reaction, Microwave assisted reactions are discussed. Different Schemes for α-aminophosphonates synthesis during recent years are discussed.
Lesions in central nervous system (CNS) and their growth leads to debilitating diseases like Multiple Sclerosis (MS), Alzheimer's etc. We developed a model earlier [6, 10] which shows how the lesion growth can be arrested through a beneficial auto-immune mechanism. The success of the approach depends on a set of control parameters and their phase space was… (More)
A novel synthetic methodology has been developed for the synthesis of diethyl 5-alkyl/aryl/heteroaryl substituted 3,4-dihydro-2H-pyrrole-4,4-dicarboxylates (also called 2-substituted pyrroline-4,5-dihydro-3,3-dicarboxylic acid diethyl esters) by iodide ion induced ring expansion of 2-[(aziridin-1-yl)-1-alkyl/aryl/heteroaryl-methylene]malonic acid diethyl… (More)
The study of the dynamics of one-dimensional chains with both harmonic and nonlinear interactions, as in the Fermi-Pasta-Ulam and related problems, has played a central role in efforts to identify the broad consequences of nonlinearity in these systems. Nevertheless, little is known about the dynamical behavior of purely nonlinear chains where there is a… (More)