T Ottone

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BACKGROUND Single nucleotide polymorphisms (SNPs) in double-strand break repair genes may alter DNA repair capacity and, in turn, confer predisposition to leukemia. We analyzed polymorphic variants of DNA repair and detoxification genes in patients with multiple sclerosis (MS) who developed secondary acute promyelocytic leukemia (sAPL), in most cases after(More)
MicroRNAs are key regulators of many biological processes, including cell differentiation. These small RNAs exert their function assembled in the RNA-induced silencing complexes (RISCs), where members of Argonaute (Ago) family of proteins provide a unique platform for target recognition and gene silencing. Here, by using myeloid cell lines and primary(More)
Since the publication of this article, the authors have identified an error within Table 2, namely that the AML subgroups listed at the bottom of the table were incorrect. The correct table is shown here. The article has also been rectified, and now carries the correct information. The Publishers apologize for any inconvenience this has caused. a TCGA b(More)
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