We report on an 80-Gbit/s 2:1 selector-type multiplexer IC using InAlAs/InGaAs/InP HEMTs incorporating a high-speed double layer interconnection process with a low permittivity insulator. The record operating data rate was measured on a 3-inch wafer. In spite of the bandwidth limitation on the measurement setup, clear eye patterns were successfully observed… (More)
This paper reviews recent advances in 40-Gbit/s class analog and digital ICs developed at our laboratories for future lightwave communications systems. A 0.1-/spl mu/m gate InAlAs/InGaAs HEMT with InP recess etch stopper was adopted mainly for IC fabrication. Fabricated ICs demonstrate excellent data-multiplexing, demultiplexing and amplifying operation at… (More)
Induced pluripotent stem cells (iPSCs) are novel stem cells derived from adult mouse and human tissues by reprogramming. Elucidation of mechanisms and exploration of efficient methods for their differentiation to functional cardiomyocytes are essential for developing cardiac cell models and future regenerative therapies. We previously established a novel… (More)
To engineer a stem cell genome, we developed a technology for targeted elimination of chromosomes from mouse embryonic stem (ES)-somatic hybrid cells. Here we demonstrate the use of a universal chromosome elimination cassette (CEC) for elimination of a single embryonic stem cell (ESC)-derived chromosome 11 or 12, and also both copies of chromosome 6, which… (More)
This paper describes a novel dynamic flip-flop (FF) circuit that can operate 30% faster than conventional clocked inverter-type FFs. A new wide-band clock buffer is introduced to cover the FF operation range. An 8- to 24-Gbit/s decision circuit and a 9- to 26-GHz 1/2 frequency divider were developed using production-level 0.2-/spl mu/m GaAs MESFET… (More)
This paper presents the recent progress of 40-Gbit/s time division multiplexing (TDM) transmission technologies based on 0.1-/spl mu/m InP HEMT ICs and new optical devices operating at 40 Gbit/s and beyond. System experiments demonstrate that the 40-Gbit/s TDM system is very attractive for upgrading transmission capacity into the Tbit/s range.
Cardiomyocytes (CMs) derived from human embryonic stem cells (hESCs) or human induced pluripotent stem cells (hiPSCs) are functionally heterogeneous, display insufficient biological efficacy and generally possess the electrophysiological properties seen in fetal CMs. However, a homogenous population of hESC/hiPSC-CMs, with properties similar to those of… (More)