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1. During just-suprathreshold synaptic activation of CA1 pyramidal cells in rat hippocampal slices in vitro the action potential begins as a slow depolarizing ramp, superimposed on the underlying EPSP and forming an integral part of the action potential. We call this ramp a synaptic prepotential (SyPP). 2. In order to examine the SyPP, a procedure for(More)
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