T. Okamoto

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The rapid development of information technology has enabled many systems that support creative work. However, it has gradually become obvious that the latest information systems have a serious drawback in that instead of promoting creative work, they often discourage it or let us stop thinking actively while doing it. In this paper, we begin by explaining(More)
AIMS/INTRODUCTION Type 2 diabetes mellitus is a progressive disease that frequently requires patients to use more than one oral antihyperglycemic agent to achieve adequate glycemic control. The present multicenter, randomized study assessed the efficacy and safety of the addition of sitagliptin to ongoing voglibose monotherapy (0.2-0.3 mg three times daily)(More)
We describe a large-scale simulation of the seismic wave propagation from the 2011 Tohoku-Oki earthquake. We combine structure models for topography, sediments, crust and subducting plates to construct a 3D structure model for the northeastern Japan area. Then we simulate the near-field wave propagation by using a FDTD method which is accelerated by the use(More)
AIMS To evaluate the efficacy and tolerability of sitagliptin in subjects with impaired glucose tolerance (IGT). METHODS In a double-blind, parallel-group study, 242 Japanese subjects with IGT, determined by a 75-g oral glucose tolerance test (OGTT) at week -1, were randomized (1 : 1 : 1) to placebo (n = 83), sitagliptin 25 mg (n = 82) or 50 mg (n = 77)(More)
Long-period ground motions in plain and basin areas on land can cause large-scale, severe damage to structures and buildings and have been widely investigated for disaster prevention and mitigation. However, such motions in ocean-bottom areas are poorly studied because of their relative insignificance in uninhabited areas and the lack of ocean-bottom(More)
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