T N Tuganova

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Routinely stained cytological preparations of puncture biopsy specimens of mediastinal tumors from 870 patients are examined. Diagnostically informative material is investigated in 759 (87.3%) cases; malignant tumors are diagnosed in 538 (62%) cases, benign in 221 (25.2%). In 59 (6.8%) cases the cytological answers were descriptive, and in 52 (6%) puncture(More)
The findings of a change in the content of the main types of nucleoli and argentophilic granules involved in the structural organization, formation of active forms allow evaluation of the efficiency of radiation exposure and its combined modes during neoadjuvant therapy for glandular breast carcinoma by cytogenetic studies. A comparative study of chromosome(More)
The complex examination of 1400 patients with pathologic masses of the lungs and mediastinal organs with the use of roentgenologic, endoscopic, puncture bioptic and cytologic methods was carried out. Morphologic verification of diagnosis was performed in 93.7% of the patients. In express cytologic study, histogenesis of neoplasms of the thoracic cavity(More)
Comprehensive approach to study nucleolar organizer region activity rating in lymphoid cells of 87 human normal lymphatic nodes was proposed. Possibility of visualization of basic morphofunctional nucleolar types and different subtypes of nucleolonemal nucleoluses was demonstrated at light microscopy level basing on 7387 prolymphocyte nucleus research of(More)
A study of argentophil granules within and outside of the nucleolonem nucleoli along the area of immature lymphoid cells (5655) revealed, in Non-Hodgkin's lymphoma and benign hyperplasia, differential-and-diagnostic, dimensional, quantitative and topographic parameters, which expand the possibilities of the cytological method in verifying reliably the(More)
Cytomorphological signs of ovarian dysherminoma are distinguished on suboperation material from 7 patients. Scrapings from removed ovarian tumors were stained after N. G. Alexeev and Pappenheim. Dysherminoma cytograms were characterized mainly by a combination of three cell types: large sharply polymorphic epithelioid with multiple clearly-seen nuclei,(More)
Expression of main morphofunctional types of blast cell nucleoli in lymphomas and benign hyperplasia was compared in the cytological material of 38 patients for revealing additional differential cytological signs of malignant transformation of lymphoid cells. Cytogenetic criteria of malignant transformation of the blast population of lymphoid cells were(More)
Qualitative differentiated study and calculation of 44404 main morphofunctional types of nucleoli has been perfomed on Ag-positive punction specimens from 50 patients with glandular breast cancer. Accordance of different for their activity morhofunctional types of nucleoli and extranucleolar argentofil granules to proliferative activity rates, malignant(More)