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Hepatoprotective effect of metabolism correctors has been studied on the model of experimental viral and toxic damage of the liver. Reamberin-based substrate compositions (cytoflavin and remaxol) exhibit antihypoxic effect, antioxidant activity, and cytoprotective action on the background of metabolic effect. Based on these results, the indicated… (More)
Positive effects of angiogen, a preparation containing succinic and acetylsalicylic acids, on ECG, blood clotting, and lipid metabolism were demonstrated on animals with experimental cardiovascular disease induced by repeated injections of norepinephrine.
It has been demonstrated in rat experiments that intraperitoneal injection of 100 mg/kg phenazepam immobilizes the animals for one hour, causes long-term diminution of the muscular tonus and disturbed coordination of movements, tachycardia, hypotension, hyperthermia, depression of orientation and exploration motor activity, and disturbance of conditioned… (More)
Experiments on rodents showed that pentifin, a muscarine antagonist belonging to the group of acetylene amines, possesses a pronounced antiparkinsonian activity. Pentifin is superior in the breadth of therapeutic action and tolerance characteristics to the conventional agents used for Parkinson's disease treatment.
It is established that remaxol influences the main links of cells antioxidant system in case of experimental drug-induced liver damage. The injection of remaxol to animals with hepatotoxic damage increases the level of restored glutathione and maintains the concentration of SH groups of proteins in liver tissues on the level typical of intact animals.… (More)