T. MacGillivray

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This paper summarizes three recent, novel algorithms developed within VAMPIRE, namely optic disc and macula detection, arteryvein classification, and enhancement of binary vessel masks, and their performance assessment. VAMPIRE is an international collaboration growing a suite of software tools to allow efficient quantification of morphological properties(More)
Social precursors to symbolic understanding of pictures were examined with 100 infants ages 6, 9, 12, 15, and 18 months. Adults demonstrated 1 of 2 stances toward pictures and objects (contemplative or manipulative), and then gave items to infants for exploration. For pictures, older infants (12, 15, and 18 months) emulated the adult's actions following(More)
Proteolytic digestion of dried bonito muscle with thermolysin produces a hydrolysate with strong angiotensin-converting enzyme (ACE) inhibitory activity and is the basis of a dietary supplement with antihypertensive activity. A major portion of the ACE activity was shown previously to arise from the peptide Leu-Lys-Pro-Asn-Met (LKPNM). A straightforward(More)
Objectives. We investigated whether ultrasmall paramagnetic particles of iron oxide- (USPIO-) enhanced magnetic resonance imaging (MRI) can detect experimental chronic allograft damage in a murine renal allograft model. Materials and Methods. Two cohorts of mice underwent renal transplantation with either a syngeneic isograft or allograft kidney. MRI(More)
Multi-parametric MR image registration combines different imaging sequences to enhance visualisation and analysis. However, alignment of the different acquisitions is challenging , due to contrast-dependent anatomical information and abundant artefacts. For two decades, voxel-based registration has been dominated by methods based on mutual information,(More)
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