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Micronuclei (MN) production in the peripheral blood T-lymphocytes of patients receiving pelvic radiotherapy for localized prostate cancer increases with increasing integral radiation dose to the prostate/pelvic area, thereby demonstrating a linear, in vivo, clinical dose response relationship for this biological dosimetry system. Use of this lymphocyte(More)
Although acute myeloid leukemia (AML) exhibits diverse responses to chemotherapy, patients harboring the t(8;21) translocation are part of a favorable risk group. However, the reason why this subgroup is more responsive to cytarabine-based therapy has not been elucidated. In the present study, we analyzed expression levels of cytarabine metabolism-related(More)
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