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The aim of this project is to acquire a direct image of histology from in vivo gastrointestinal mucosa. In other words, the task of 'endo-microscope' is to observe the cellular architecture of tissue in vivo during routine endoscopic examination. As the first step to completing this study, resected fresh specimens from the oesophagus. stomach and colon were(More)
A catheter-type endomicroscope has been developed with a maximum magnifying power of 1100 times. Living cancer cells in the esophagus, stomach, and colon were successfully observed in high-resolution images. The "Endo-Cytoscopy system" (prototype,Olympus Optical, Co., Tokyo, Japan) is a catheter-based probe capable of passage through the accessory channel(More)
Osteoporosis is often present in postmenopausal women. The aim of this retrospective cohort study was to assess the cumulative incidence and predictive factors for bone fracture after cessation of interferon (IFN) in postmenopausal women with osteoporosis and chronic liver disease caused by hepatitis C virus (HCV). A total of 420 postmenopausal women(More)
BACKGROUND AND STUDY AIMS We have previously reported the success of a method of virtual histology using laser-scanning confocal microscopy (LCM) in vitro on untreated fresh specimens obtained from the gastrointestinal mucosa. In the present study, we aimed to apply LCM to both fresh and formalin-fixed specimens, without additional treatment, in order to(More)
Our treatment strategy for esophageal cancer is as follows; mucosal cancer with the minimal risk of lymph node metastasis is treated by endoscopic mucosal resection (EMR). Submucosal cancer and more invasive lesions are surgically treated by thoraco- and aparoscopy-assisted esophagectomy. In May 1997, the first case received totally endoscopic(More)
We report an approach to estimate the functional connection from the possible anatomical connections and physiological response of each neuron. Here we focus on the brain of Bombyx mori, a male silkmoth, which exhibits a programmed behavior for the pheromone orientation on a pheromone detection. The neuroethological experiments revealed that the motor(More)
Male silkmoth is known for its programmed behavior for the pheromone orientation on the pheromone source detection. Estimation of the functional connection is done based on the possible anatomical connections and physiological response of each neuron. The action command is generated in the premotor center, composed of the lateral accessory lobe (LAL) and(More)
Malformations of the esophagus are very rare . We experienced a case of malformation of the lower part of the esophagus extending to the cardia. We can not find similar case in the l i terature. A 45-year-old man had complained of feel ing of retention of food in the lower part of esophagus which had continued for 30 seconds af ter swallowing. Previous(More)
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