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The effects of tree height on shoot traits may in some cases differ in magnitude and direction from the effects of light. Nevertheless, general patterns of change in shoot traits in relation to variations in height and light have not so far been revealed. A comprehensive analysis of the differences between the effects of height and light on a range of leaf(More)
Polysialic acid is a developmentally regulated carbohydrate attached to the neural cell adhesion molecule, N-CAM, and abundant in embryonic tissues. There is increasing evidence that polysialic acid reduces N-CAM adhesion, thereby promoting neurite outgrowth and cellular mobility. It has been shown that two enzymes, polysialyltransferase, PST, and(More)
In reverse genetics, a gene's function is elucidated through targeted modifications in the coding region or associated DNA cis-regulatory elements. To this purpose, recently developed customizable transcription activator-like effector nucleases (TALENs) have proven an invaluable tool, allowing introduction of double-strand breaks at predetermined sites in(More)
Following tissue damage the immune response, including inflammation, has been considered an inevitable condition to build the host defense against invading pathogens. The recruitment of innate immune leukocytes to injured tissue is observed in both vertebrates and invertebrates. However, it is still not conclusive whether the inflammatory response is also(More)
(Shaked etal., PLoS ONE 2008). To further investigate this finding, several different approaches have been taken. First, the expression of HDAC-regulated candidate genes responsible for controlling neurogenesis has been examined through quantitative real-time RT-PCR. TSA-based inhibition of HDAC activity resulted in upregulation of Bmp2, Stat1, Stat3, Ngn1(More)
We studied the ontogeny of the rat parietal cell using human anti-parietal cell antibody and transmission electron microscopy. In the gastric fundus of the rat, we found that the epithelium changed from stratified to columnar at gestational day 18.5. Gastric pits began to form at gestational day 19.5. Primitive fundic glands appeared at gestational day(More)
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