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The anti-apoptotic protein, BAX inhibitor-1 (BI-1), has a role in cancer/tumor progression. BI-1-overexpressing HT1080 and B16F10 cells produced higher lung weights and tumor volumes after injection into the tail veins of mice. Transfection of BI-1 siRNA into cells before injection blocked lung metastasis. in vitro, the overexpression of BI-1 increased cell(More)
Herein we report a case of encephalitis involving the unilateral hemisphere, with a clinical course different from that of Rasmussen syndrome. A 44-year-old man visited us because of headache and language abnormality. Cerebrospinal fluid examination showed lymphocytosis with increased level of protein. Brain MRI showed abnormal findings limited to the(More)
Met is a receptor tyrosine kinase that promotes cancer progression. In addition, Met has been implicated in resistance of tumors to various targeted therapies such as epidermal growth factor receptor inhibitors in lung cancers, and has been prioritized as a key molecular target for cancer therapy. However, the underlying mechanism of resistance to(More)
We report a young woman with pancytopenia and huge splenomegaly who was also found to have peripheral T-cell lymphoma with massive infiltration of T-cell evident in the liver and spleen. A liver biopsy showed predominant sinusoidal infiltration of pan-T cell antibody-stained T-lymphoid cells. Histologic examination of the spleen revealed numerous tumor(More)
A novel mode analysis method and differential mode delay (DMD) measurement technique for a multimode optical fiber based on optical frequency domain reflectometry has been proposed for the first time. We have used a conventional OFDR with a tunable external cavity laser and a Michelson interferometer. A few-mode optical multimode fiber was prepared to test(More)
We present a low coherent hybrid detection technique for the differential model delay (DMD) measurement of a conventional optical multimode fiber with a modified Mach-Zehnder interferometer. A low coherent hybrid detection technique enhances mode coupling between guided modes and the reference mode to easily resolve the modal distribution. An optical(More)
A novel differential mode delay (DMD) measurement technique for a multimode optical fiber based on optical frequency domain reflectometry (OFDR) has been proposed. We have obtained a high-resolution DMD value of 0.054 ps/m for a commercial multimode optical fiber with length of 50 m by using a modified OFDR in a Mach-Zehnder interferometer structure with a(More)
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