T. I. Skudarnova

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It was previously shown [1-4] that the heterocyclization of the 1,3-dimethyl-5-cyanacetyl-6-aminouracils (I)-(VI) in an alkaline or acidic medium leads to the 7-aminoor 7-hydroxypyrido[2,3-d]pyrimidines correspondingly. With the object of isolating compounds with potential antibacterial activity, we continued the study of the chemical properties of the(More)
A number of [2,3-d]pyrimidine derivatives have diuretic activity [8, 9]. We describe here the synthesis o f previously unknown 7-acylamino and 6-nitro-7-acylamino derivatives based on available 1,3-disubstituted 7-aminopyrido[2,3-d]pyrimidine2,4,5-triones (I) [5-7] and studies of their diuretic activity. Previous studies have shown that electrophilic(More)
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