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OBJECTIVE To investigate the correlation between Electrogastrography (EGG) and the occurrence of nausea or/and vomit as well as the development of motion sickness (MS) induced by optokinetic stimulation (OPS) and to provide a clue and method for prediction and prevention of MS. METHOD Twenty male subjects, aged from 18 to 25 years, performed the test only(More)
Vection alone, or combined with head movements, has been shown to invoke motion sickness (MS). This study's purpose was to observe how different combinations of vection and head movements influenced the severity of MS. We tested 26 subjects in a rotating sphere at a speed of 45 degrees/s, resulting in vertical yaw, horizontal roll or pitch vection.(More)
Space motion sickness (MS) is one of the most important problems in the field of space medicine. In order to prevent space MS, a new medicine, PMPA, has been prepared by means of synthesizing in our laboratory. The purposes of this study were to set up animal models of PMPA against MS, and to observe its effects on anti-MS, and to prove its function of(More)
The protein serine/threonine phosphatases-1 and -2A are major cellular phosphatases, playing a fundamental role in organisms from prokaryotes to eukaryotes. They contribute to 90% dephosphorylation in eukaryote proteins. In the eye, both phosphatases are highly expressed and display important functions in regulating normal eye development. Moreover, they(More)
Thermal emergency situations have more than once been encountered since the beginning of manned space flights in 1961. This article contemplates human thermal tolerance in weightlessness as complicated with headward [correction of headword] fluid shifts, plasma volume loss, cardiovascular deconditioning, reduced exercise capacity and energy metabolism(More)
OBJECTIVE To analyze the thermal physiological changes of man in a Intravehicular Activity (IVA) space suit. METHOD Combined second design was used to arrange 24 tests in 6 young male subjects wearing an IVA space suit at sea level. RESULT The relationship between common thermal physiological measurements and air ventilating parameters (air temperature,(More)
The protein phosphatase-2A (PP-2A) is one of the most important serine/threonine phosphatases in eukaryotes. The holoenzyme of PP-2A consists of three subunits: a scaffold A subunit, a catalytic C subunit and a regulatory B subunit. While both A and C subunits are coded by two different genes, the B subunits exist in 26 or more isoforms which are encoded by(More)
OBJECTIVE To explore a space craft precooling temperature at which excessive thermal stress on the crew member could be prevented or reduced in an overheated launch or reentry module. METHOD Five young male volunteers wearing a space suit participated in 25 tests at sea level. The space suit was either ventilated in a volume air flow rate of 100 L/min(More)
Comparisons of headward fluid shifts, plasma volume losses, altered vasodilator and vasoconstrictor responses, reduced exercise capacities, etc. between microgravity and head-down tilt (HDT) bedrest suggested that HDT model was suitable for simulating thermoregulation under microgravity. Both microgravity and simulated microgravity by HDT exposures degraded(More)
Sumoylation, a post-translational modification discovered over a decade ago, turns out to be a very important regulatory mechanism mediating multiple cellular processes. Recent studies from our laboratory and others also revealed that it plays a crucial role in regulating both differentiation and pathogenesis of the ocular lenses. This review will summarize(More)