T. F. Vlasova

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The free amino acid pool of blood of man exposed to 120-day head-down tilt (at -4 degrees) was examined. Beginning with bed rest day 28 and till the end of the study, the amino acid pool increased. The increase involved most free amino acids which was produced by a decline of anabolic and stimulation of catabolic processes during hypokinesia.
The present investigation presents results of studying free amino acids of peripheral plasma in cosmonauts who made space flights of different duration onboard the spacecraft Soyuz-12, Soyuz-16 and the orbital station Salyut-4. The study showed changes in the content of free amino acids which varied for different amino acids. Most pronounced changes were(More)
The plasma alanine concentration was measured in 28 healthy male test subjects exposed to head-down tilt of various duration (2-hour exposure at-12 degrees, 7-day exposure at-6 degrees, 49-day exposure at-4 degrees, and 120-day exposure at-4 degrees). Head-down tilt led to alanine changes that correlated with exposure time. These results suggest that(More)
Taking into consideration metabolic specificities of cosmonauts, the data on their amino acid composition during preflight training were summarized. Seasonal variations produced no effect on the content of free amino acids of plasma. The analysis yielded a physiological norm for this population which can be used to identify more reliably changes in the(More)
Skeletal muscles of flight rats showed no changes in the content of glycogen, adenosine triphosphatase activity of myosin and protein content in protein fractions (except the T fraction where the protein content increased on the 1st and returned to the normal on the 26th postflight day). On the 1st postflight day activities of aminotransferases and lactate(More)
The content of free amino acids (valine and arginine) and their ratio (V/A ratio) in the blood plasma was studied in men (4 groups each holding 5 persons) kept on controlled diets with varying content of protein nitrogen. The experiments made it possible to reveal definite changes in the V/A ratio depending on the amount of protein nitrogen in the diet. The(More)
The content of free amino acids was measured in the blood serum of 6 male test subjects exposed to 7-day immersion. During the study the concentration of amino acids decreased in a different manner typical of a stress-effect. The results obtained can be used to develop a system of prevention and therapy of amino acid unbalance.
The effect of different levels of protein in he diets (15.1 +/- 0.3; 9.4 +/- 0.2; 8 +/- 0.4; 4.6 +/- 0.3 g nitrogen a day) on assimilation of amino acids in man was studied. The rates of endogenous excretion of 18 amino acids with feces were determined in the course of protein-free nutrition. It has been shown that as the body supply with protein decrease(More)
The biological value of the protein component of three modifications of the Salyut space diet was measured in laboratory studies and in simulated space flights. Three experimental runs of up to 68 days in duration were carried out on 20 volunteers. During the study the following parameters of protein metabolism were measured: total protein and protein(More)