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PURPOSE To investigate the efficacy of gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) in the detection of focal liver lesions with respect to dose, side effects, and pulse sequence. MATERIALS AND METHODS A randomized double-blinded trial was performed in 33 patients with focal solid liver lesions. A bolus of Gd-EOB-DTPA, a(More)
PURPOSE To investigate the superparamagnetic iron oxide (Resovist) designed for contrast material-enhanced magnetic resonance imaging of the liver. MATERIALS AND METHODS A phase 2 trial was performed in 33 patients with no more than five known focal solid liver lesions. Resovist was administered intravenously at doses of 4, 8, and 16 mumol of iron per(More)
The purpose of this study was to investigate whether MR angiography (MRA) of the portal venous system may be improved by means of superparamagnetic iron oxides (SPIOs) during accumulation phase imaging and to study the underlying contrast mechanisms. MRA of the portal venous system was performed on 48 patients before and after intravenous injection of a new(More)
OBJECTIVE To report the long term results of abdominal rectopexy in patients with complete rectal prolapse. DESIGN Ongoing prospective randomised study. SETTING Department of Surgery, Westfälische Wilhelms-University, Münster. SUBJECTS 47 patients with complete rectal prolapse operated on between 1982 and 1989. INTERVENTIONS Abdominal rectopexy with(More)
BACKGROUND Splenectomy is the therapy of choice after relapse following different immunosuppressive treatments for idiopathic thrombocytopenic purpura, which is still the most frequent cause of thrombocytopenia. STUDY DESIGN A prospective clinical study was undertaken to evaluate the rate of complete remission in idiopathic thrombocytopenic purpura after(More)
Between July 1990 and September 1993, 32 patients with locally advanced irresectable adenocarcinoma of the pancreas, histologically proven by laparotomy, were involved in our study. Patients were treated with hyperfractionated, accelerated radiotherapy and simultaneous application of 5-fluorouracil and folinic acid. Chemotherapy was given on days 1,2 and 3.(More)
Although gray and white matter are distinguished by computed tomography (CT) in the cerebrum and cerebellum, their resolution in the mesencephalon has not been reported. CT and anatomic sections of the mesencephalon were compared to determine the relative densities of the superior cerebellar peduncles (white matter) and red nuclei and central gray matter.(More)
38 patients with advanced oesophageal carcinoma were treated with intravenous (i.v.) folinic acid (300 mg/m2), 5-fluorouracil (500 mg/m2), etoposide (100 mg/m2), and cisplatin (30 mg/m2) (FLEP), on days 1, 2 and 3, every 22-28 days. 26 patients had locally advanced disease (LAD) and 12 had metastatic disease (M1). Oesophagectomy was planned for patients(More)
In a specific animal model the induction of heterologous enchondral ossification was examined in long term follow-up. Physiologically normal and devitalized frozen porcine epiphyseal cartilage as a control group were transplanted as s.c. xenograft into athymic nude mice (nu/nu). 15 weeks after transplantation the porcine growth plate cartilage showed the(More)
Using a CT/T 8800 scanner, axial and coronal images of the optic chiasm were obtained in a cadaver, 41 normal individuals, and six patients with symptoms of chiasmal glioma. The size and shape of each chiasm were determined. The normal chiasm appeared to be U- or boomerang-shaped in axial sections, and U- or dumbell-shaped in coronal sections. The average(More)