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Journals and Conferences
In spite of intensive antimicrobial prophylaxis and therapy, most patients with acute radiation sickness I-IV severity grade (dose of 0.1-13.7 Gy) developed infections caused by bacteria, fungi and viruses. Frequency and intensity of those infections were proportional to the radiation dose and severity grade of radiation sickness.
Experiments on 2,520 CBA mice (CBA X X C57BL) F1 nice have shown that the injection of homologous serum immunoglobulins (obtained from intact and blood-stimulated animals), made 2 hours after gamma irradiation from a 60Co source, prevents the development of intestinal dysbacteriosis and endogenous infection. The injection of mouse and human immunoglobulins… (More)
It was shown in experiments with mice and dogs that bacterial preparations (vaccinum proteus, prodigiosanum, bificolum and bificolum-f) administered before or after gamma-irradiation have a stimulating effect on hemopoiesis. It is supposed that bacterial polysaccharides play an important role in this action.
In experiments with three species of animals (mice, rabbits, monkeys) irradiated with sublethal and lethal doses of gamma-irradiation, it was observed, that leukinferon used in 4 hours or 10 days after provided antiradiation therapeutical effect. When lethal dose was used (mice) the survival of animals was significantly increased. The preparation decreased… (More)
Humoral and cellular factors of the immune system of 133 subjects injured in the Chernobyl accident were studied during first 1.5-2 months after radiation, 5-17 months and 3 years after they suffered acute radiation sickness (I-IV degree). Significant disorders in the immune system correlating with the severity of the disease were recorded. In late terms… (More)